Arora Prem, Kalra Vaneet Kumar, Rane Sharayu, McGrath Eric J, Zegarra-Linares Ricardo, Chawla Sanjay
The Carman and Ann Adams Department of Pediatrics, Division of Infectious Diseases, Wayne State University, School of Medicine, Detroit Medical Center, Children's Hospital of Michigan, Detroit, Michigan, United States.
BMJ Case Rep. 2011 Dec 21;2011:bcr0820114733. doi: 10.1136/bcr.08.2011.4733.
A preterm neonate was noted to have diffuse blanching erythema around the mouth followed by appearance of bullous lesions on the upper back, lower neck and right scapular areas at 23 h of life. The bullae subsequently ruptured leaving an extremely tender, erythematous, denuded area of the skin, which extended over next few hours to involve most of the upper back and right shoulder regions. Nikolsky sign was positive. Clinical diagnosis of staphylococcal scalded skin syndrome was made. The throat, blood, urine and cerebrospinal fluid cultures did not yield any growth, but wound culture was positive for Staphylococcus aureus. Treatment included administration of intravenous fluids and vancomycin for 10 days. The wound area was covered with vaseline and sterile gauge dressings. On day 5 of life, epithelialisation began and was complete on the seventh day of life. She was discharged home with intact skin, without scars, on day 12 of life.
一名早产儿在出生23小时时，被发现口周有弥漫性苍白性红斑，随后在上背部、下颈部和右肩胛区出现大疱性皮损。大疱随后破裂，留下极其 tender、红斑性、皮肤剥脱的区域，在接下来的几个小时内扩展至累及大部分上背部和右肩部区域。尼氏征阳性。做出了葡萄球菌烫伤样皮肤综合征的临床诊断。咽喉、血液、尿液和脑脊液培养均未生长出任何细菌，但伤口培养金黄色葡萄球菌呈阳性。治疗包括静脉补液和使用万古霉素10天。伤口区域用凡士林和无菌纱布敷料覆盖。出生第5天开始上皮化，出生第7天完成。她在出生第12天皮肤完好、无瘢痕地出院回家。
