Bobek P, Ginter E, Jurcovicová M, Ozdín L, Cerven J, Babala J
Research Institute of Human Nutrition, Bratislava, Czechoslovakia.
Nahrung. 1990;34(9):783-9. doi: 10.1002/food.19900340902.
The effect of two dehydrated apple products (10% in diet)--apple pulp (crude fibre 3.5%, pectin 1.4%) and apple pomaces (crude fibre 13.5%, pectin 7%)--on the serum and liver lipids of growing Syrian male hamsters were studied. The animals were fed a natural diet (38% of energy substituted by milk fat; the diet contains 53 mg of cholesterol (CH) per 100 g) which resulted in an accumulation of CH and triacylglycerols (TG) in the serum as well as in the liver, and CH-rich very low density lipoproteins (VLDL) in the circulation. After two months both apple products decreased the levels of CH and TG in serum (by 40-70%) and the content of CH in VLDL with similar efficiency. Both products reduced CH content in the liver, and the apple pulp also decreased TG content. Up to the 6th month the apple pulp studied suppresses accumulation of CH and TG in both the serum and the liver. A complete analysis of lipoproteins of main density class at the time showed that the decrease of serum CH and TG to a decisive extent is due to the decrease of their concentration in VLDL (by more than 50%). Therefore, the concentration of VLDL and the whole lipoprotein pool decreased by 50%. The apple pulp doubled the amount of CH transported by HDL. Three months after the replacement of butter in the diet by corn germ oil the CH and TG levels in the serum and TG also in the liver decreased to the physiological level.(ABSTRACT TRUNCATED AT 250 WORDS)
研究了两种脱水苹果产品（日粮中占10%）——苹果果肉（粗纤维3.5%，果胶1.4%）和苹果渣（粗纤维13.5%，果胶7%）对生长中的叙利亚雄性仓鼠血清和肝脏脂质的影响。给动物喂食天然日粮（38%的能量由乳脂肪替代；日粮每100克含53毫克胆固醇（CH）），这导致血清和肝脏中CH和三酰甘油（TG）积累，以及循环中富含CH的极低密度脂蛋白（VLDL）。两个月后，两种苹果产品均以相似效率降低了血清中CH和TG水平（降低40 - 70%）以及VLDL中的CH含量。两种产品都降低了肝脏中的CH含量，苹果果肉还降低了TG含量。直至第6个月，所研究的苹果果肉抑制了血清和肝脏中CH和TG的积累。当时对主要密度类别的脂蛋白进行的全面分析表明，血清CH和TG的降低在很大程度上是由于它们在VLDL中的浓度降低（超过50%）。因此，VLDL浓度和整个脂蛋白池降低了50%。苹果果肉使HDL转运的CH量增加了一倍。用玉米胚芽油替代日粮中的黄油三个月后，血清中的CH和TG水平以及肝脏中的TG水平也降至生理水平。（摘要截取自250字）
