Sicart R, Sablé-Amplis R
Ann Nutr Metab. 1987;31(1):1-8. doi: 10.1159/000177242.
The influence of an apple-supplemented diet on the distribution of cholesterol among the lipoproteins in plasma was studied using a special animal model: FEC hamsters which spontaneously develop hypercholesterolemia with aging when fed a commercial balanced diet. This metabolic disorder did not occur in animals freely consuming apples in addition to the standard diet. This combined diet essentially decreased the cholesterol content in the VLDL and LDL, the apo B-rich lipoproteins in plasma.
使用一种特殊的动物模型——FEC仓鼠，研究了添加苹果的饮食对血浆脂蛋白中胆固醇分布的影响。当给FEC仓鼠喂食商业均衡饮食时，它们会随着年龄的增长自发出现高胆固醇血症。而在标准饮食之外自由食用苹果的动物则未出现这种代谢紊乱。这种组合饮食从本质上降低了血浆中富含载脂蛋白B的极低密度脂蛋白（VLDL）和低密度脂蛋白（LDL）中的胆固醇含量。
