Department of Mechanical Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, USA.
Skin Res Technol. 2013 Feb;19(1):e339-48. doi: 10.1111/j.1600-0846.2012.00649.x. Epub 2012 Jun 7.
BACKGROUND/PURPOSE: Existing skin mechanical testing devices focus on measuring skin elasticity and are not tailored to assess the dynamic behavior of skin. Additionally, the mathematical techniques used in existing devices are often not optimal.
A new dynamic mechanical device that measures the linear dynamics of skin was developed and tested. The mechanical properties of skin were evaluated in experiments in which stiffness and damping parameters were measured (i) at different locations on the arm and hand, (ii) when stratum corneum hydration was varied by controlled changes in environmental humidity, and (iii) following the application of film-forming polymers. Parallel measurements were made with the Cutometer so that the two devices could be compared.
The findings revealed that reliable and valid measurements of skin mechanical properties can be obtained from the device. The stiffness of the skin was shown to vary significantly as a function of skin site, changes in stratum corneum hydration and following application of the polymer films. Changes in the damping parameter were less consistently associated with varying the condition of the skin.
The high reliability and speed of measurement make this device and analytic procedure an attractive option for testing skin mechanics.
背景/目的:现有的皮肤机械测试设备主要关注测量皮肤弹性,而不是针对评估皮肤的动态行为进行定制。此外,现有设备中使用的数学技术往往不是最佳的。
开发并测试了一种新的测量皮肤线性动力学的动态机械装置。通过实验评估了皮肤的机械性能,在这些实验中测量了(i)手臂和手部不同位置的刚性和阻尼参数,(ii)通过控制环境湿度来改变角质层水合作用时,以及(iii)在应用成膜聚合物后。使用 Cutometer 进行平行测量,以便对两种设备进行比较。
研究结果表明,可以从该设备获得皮肤机械性能的可靠和有效的测量值。皮肤的刚性被证明是作为皮肤部位、角质层水合作用变化以及聚合物膜应用后的函数而显著变化。阻尼参数的变化与皮肤状况的变化关联不大。
测量的高可靠性和速度使该设备和分析程序成为测试皮肤力学的有吸引力的选择。