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经皮肾镜微造瘘治疗肾结石——单中心经验及文献综述

Mini-Perc for Renal Stones-A Single Center Experience and Literature Review.

作者信息

Cauni Victor-Mihail, Dragutescu Mihai, Mihai Bogdan, Gorecki Gabriel-Petre, Ples Liana, Sima Romina-Marina, Persu Cristian

机构信息

Department of Urology, Colentina Clinical Hospital, 020125 Bucharest, Romania.

Department of Anesthesia and Intensive Care, CF2 Clinical Hospital, 011464 Bucharest, Romania.

出版信息

Diagnostics (Basel). 2023 Mar 13;13(6):1083. doi: 10.3390/diagnostics13061083.

Abstract

AIM

The aim of this study was to analyze the outcomes of miniaturized nephrolithotomy (mini-perc) in the management of renal stones with a diameter smaller than 20 mm.

MATERIALS AND METHODS

We retrospectively reviewed the records of 102 patients who underwent mini-perc between March 2015 and March 2020 in our department. The primary objective was the stone-free rate, but we also analyzed the retreatment rate, complications, hospital stay, operative time and reduction in hemoglobin level. All these patients had this technique as their first-line treatment, in a prone position, using a 16 Fr sheath size. Data were compared to a series of patients from the literature, treated with conventional PCNL.

RESULTS

The patients had calculus limited to either a single calyx or just extending to the renal pelvis, and stone size was less than 20 mm in its maximal dimension. The intrarenal stone location was in the upper calyx in 7 cases, middle calyx in 20 cases and lower calyx in 46 cases, and there were 29 patients with renal pelvis stone. The male to female ratio was 1.5:1, and the median age was 48.4 years. The average stone size was 17.4 mm in diameter (ranging between 9 and 20 mm) and all cases underwent Ho-YaG laser lithotripsy, ballistic energy and combined ultrasonic and ballistic lithotripsy. At the end of the procedure, an antegrade double J stent was placed under fluoroscopy for a maximum of 2 weeks in 42 cases, while 9 cases needed a nephrostomy tube 12-14 F. A total of 51 cases were totally tubeless. Our median operative time was 61 min (ranging from 35 to 75 min). The median hospitalization stay was 3.8 days. The stone free rate was 90.1% after one procedure, only nine (8.8%) cases needed a "second look" flexible ureteroscopy, and the final stone-free rate was 98% (absence of detectable calculi on ultrasound, KUB or non-contrast CT scan). The overall complication rate was 6.86% (Clavien classification I-57.14%; II-28.5%; III-14.2%), while no Clavien IV or V complications were reported. No patient required a blood transfusion, and mean hemoglobin loss was 0.81 mg/dL. Overall, our results are better than similar data for conventional PCNL in the literature.

CONCLUSIONS

The "mini-perc" technique is an effective procedure for the treatment of the renal lithiasis that is less or equal to 2 cm. The results demonstrated that this minimally invasive technique is associated with a higher stone-free rate and minimal complications.

摘要

目的

本研究旨在分析小型化肾切开取石术(mini-perc)治疗直径小于20mm肾结石的效果。

材料与方法

我们回顾性分析了2015年3月至2020年3月在我科接受mini-perc手术的102例患者的记录。主要观察指标为结石清除率,但我们也分析了再次治疗率、并发症、住院时间、手术时间及血红蛋白水平下降情况。所有这些患者均将该技术作为一线治疗方法,采用俯卧位,鞘管尺寸为16F。将数据与文献中一系列接受传统经皮肾镜取石术(PCNL)治疗的患者进行比较。

结果

患者结石局限于单个肾盏或仅延伸至肾盂,结石最大直径小于20mm。肾内结石位于上盏7例,中盏20例,下盏46例,肾盂结石29例。男女比例为1.5:1,中位年龄为48.4岁。平均结石直径为17.4mm(范围9至20mm),所有病例均接受钬激光碎石、弹道能量碎石以及超声联合弹道碎石。手术结束时,42例患者在透视引导下顺行置入双J管,最长留置2周,9例患者需要留置12-14F肾造瘘管。共有51例患者完全无管化。我们的中位手术时间为61分钟(范围35至75分钟)。中位住院时间为3.8天。单次手术后结石清除率为90.1%,仅9例(8.8%)患者需要“二期”软性输尿管镜检查,最终结石清除率为98%(超声、腹部平片或非增强CT扫描未发现可检测到的结石)。总体并发症发生率为6.86%(Clavien分级:I级-57.14%;II级-28.5%;III级-14.2%),未报告Clavien IV级或V级并发症。无患者需要输血,平均血红蛋白丢失为0.81mg/dL。总体而言,我们的结果优于文献中传统PCNL的类似数据。

结论

“mini-perc”技术是治疗直径小于或等于2cm肾结石的有效方法。结果表明,这种微创技术结石清除率更高,并发症更少。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d7dd/10047343/a2c7f598133a/diagnostics-13-01083-g001.jpg

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