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两种方法治疗小儿 1-2cm 肾结石的比较:微通道经皮肾镜取石术和输尿管软镜碎石术。

Comparison of two methods for treatment of 1-2 cm kidney stones in pediatric patients: mini PCNL and RIRS.

机构信息

Department of Urology, Baskent University, Alanya A&R Center, Antalya, Türkiye.

Department of Urology, Adana City Training and Research Hospital, Health Sciences University, Adana, Türkiye.

出版信息

Langenbecks Arch Surg. 2024 Jul 8;409(1):207. doi: 10.1007/s00423-024-03402-z.

DOI:10.1007/s00423-024-03402-z
PMID:38976070
Abstract

OBJECTIVE

This study aimed to compare the results of retrograde intrarenal surgery (RIRS) and mini-percutaneous nephrolithotomy (mini-PCNL) for the treatment of 1-2 cm kidney stones in pediatric patients.

METHODS

The records of patients under the age of 18 years who were diagnosed with unilateral 1-2 cm kidney stones for the first time and underwent endoscopic surgery between February 2008 and April 2022 were retrospectively examined. The patients were divided into two groups: mini-PCNL and RIRS surgery. Parameters such as age, gender, number of stones, side, size and localization were examined. The main endpoint of the study was to compare stone-free rates (SFR) one month after both surgeries. Surgery and fluoroscopy times, postoperative hospital stay, hemoglobin decrease and complication rates were compared between the groups. SFR was evaluated one month after surgery by direct urinary system radiography and USG or CT.

RESULTS

A total of 58 patients were included in the study. There were 35 patients in the mini-PCNL group and 23 patients in the RIRS group. Table 1 shows the demographic and clinical characteristics of both groups. There was no significant difference between the groups in terms of age, gender, stone size, location, side and density. Calcium oxalate stones were observed at a higher rate in both groups. Mean fluoroscopy time was higher in the mini-PCNL group (p = 0.001). The mean surgery time was lower in the mini-PCNL group (p = 0.024). The mean hemoglobin decrease was greater in the percutaneous group (p = 0.039). There were no differences between the groups in terms of postoperative hospital stay, complication rates, and SFR one month after surgery.

CONCLUSION

Although mini-PCNL seems to be more advantageous in terms of operation time compared to RIRS, it is disadvantageous in terms of average fluoroscopy time, radiation received and average hemoglobin decrease.

摘要

目的

本研究旨在比较逆行肾内手术(RIRS)和小经皮肾镜取石术(mini-PCNL)治疗儿童 1-2cm 肾结石的结果。

方法

回顾性分析 2008 年 2 月至 2022 年 4 月期间因单侧 1-2cm 肾结石首次诊断为肾结石且接受内镜手术的 18 岁以下患者的病历。将患者分为两组:mini-PCNL 组和 RIRS 手术组。检查年龄、性别、结石数量、侧别、大小和定位等参数。研究的主要终点是比较两种手术一个月后的无结石率(SFR)。比较两组间手术时间和透视时间、术后住院时间、血红蛋白下降和并发症发生率。术后一个月通过直接尿路造影和 USG 或 CT 评估 SFR。

结果

共纳入 58 例患者,其中 mini-PCNL 组 35 例,RIRS 组 23 例。表 1 显示了两组的人口统计学和临床特征。两组在年龄、性别、结石大小、位置、侧别和密度方面无显著差异。两组均以草酸钙结石为主。mini-PCNL 组透视时间平均较高(p=0.001)。mini-PCNL 组手术时间平均较低(p=0.024)。经皮组平均血红蛋白下降较多(p=0.039)。两组术后住院时间、并发症发生率和术后一个月 SFR 无差异。

结论

虽然与 RIRS 相比,mini-PCNL 在手术时间方面似乎更有优势,但在平均透视时间、辐射量和平均血红蛋白下降方面处于劣势。

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本文引用的文献

1
Use of retrograde intrarenal surgery (RIRS) compared with mini-percutaneous nephrolithotomy (mini-PCNL) in pediatric kidney stones.经皮肾镜碎石术(PCNL)与逆行输尿管软镜碎石术(RIRS)治疗儿童肾结石的比较。
World J Urol. 2022 Dec;40(12):3083-3089. doi: 10.1007/s00345-022-04186-x. Epub 2022 Oct 16.
2
Role of Mini-Percutaneous Nephrolithotomy in the Management of Pediatric Stone Disease: A Systematic Review of Literature.微创经皮肾镜取石术在小儿结石病治疗中的作用:文献系统评价。
J Endourol. 2021 May;35(5):728-735. doi: 10.1089/end.2020.0743. Epub 2020 Dec 16.
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Which is the best treatment of pediatric upper urinary tract stones among extracorporeal shockwave lithotripsy, percutaneous nephrolithotomy and retrograde intrarenal surgery: a systematic review.
体外冲击波碎石术、经皮肾镜取石术和逆行性肾内手术治疗小儿上尿路结石的最佳治疗方法:系统评价。
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Retrograde intrarenal surgery or percutaneous nephrolithotomy: Which one is more effective for 1-2 cm renal stones in pediatric patients?逆行性肾内手术或经皮肾镜取石术:哪一种对小儿患者 1 - 2 厘米肾结石更有效?
Arch Esp Urol. 2019 Jan;72(1):54-60.
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Percutaneous nephrolithotomy versus retrograde intrarenal surgery for pediatric patients with upper urinary stones: a systematic review and meta-analysis.经皮肾镜碎石术与逆行性肾内手术治疗上尿路结石患儿:系统评价和荟萃分析。
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Clinical efficacy of percutaneous nephrolithotomy versus retrograde intrarenal surgery for pediatric kidney urolithiasis: A PRISMA-compliant article.经皮肾镜取石术与逆行肾内手术治疗小儿肾结石的临床疗效:一篇符合PRISMA标准的文章。
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Comparison of Mini-percutaneous Nephrolithotomy and Retrograde Intrarenal Surgery in Preschool-aged Children.学龄前儿童微创经皮肾镜取石术与逆行肾内手术的比较
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Comparison of Retrograde Intrarenal Surgery and Micro-Percutaneous Nephrolithotomy in Moderately Sized Pediatric Kidney Stones.逆行性肾内手术与微通道经皮肾镜取石术治疗中等大小儿童肾结石的比较
J Endourol. 2016 Jul;30(7):765-70. doi: 10.1089/end.2016.0043. Epub 2016 Apr 28.
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Arch Esp Urol. 2016 Mar;69(2):67-72.
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