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比较微经皮肾镜取石术和逆行性肾内手术在儿童肾结石患者中的结果。

A comparison of micro-PERC and retrograde intrarenal surgery results in pediatric patients with renal stones.

机构信息

Department of Urology, School of Medicine, Gaziantep University, Gaziantep, Turkey.

Department of Urology, School of Medicine, Gaziantep University, Gaziantep, Turkey.

出版信息

J Pediatr Urol. 2017 Dec;13(6):619.e1-619.e5. doi: 10.1016/j.jpurol.2017.04.022. Epub 2017 Jun 19.

Abstract

INTRODUCTION

With advancements in endoscopic surgery, open surgical techniques for urinary system stones have paved the way for the application of less invasive treatment modalities in patients with pediatric kidney stone disease. These treatment options include extracorporeal shock wave lithotripsy (ESWL), percutaneous nephrolithotomy (PCNL), and retrograde intrarenal surgery (RIRS).

OBJECTIVE

We aimed to compare the efficacy and safety of RIRS and micro-PCNL techniques in the surgical treatment of kidney stones in pediatric patients.

STUDY DESIGN

A total of 48 pediatric patients, who underwent RIRS or micro-PERC for pediatric kidney stone disease, were retrospectively analyzed. Urinalysis, urine culture, serum creatinine (Cr), blood urea nitrogen (BUN), calcium, phosphorus, parathyroid hormone, 24-hour urine sample, complete blood count (CBC), urinary system X-ray, kidney ureter bladder (KUB), and urinary system ultrasonography (USG) test results were evaluated prior to the procedure. Intravenous pyelography (IVP), non-contrast computed tomography (CT), and renal scintigraphy evaluations were also performed, if necessary. The patients were divided into two groups: micro-PERC group (n = 25) and RIRS group (n = 23). Data relating to the duration of the operation, duration of fluoroscopy, length of hospitalization, complication rates, and stone-free rates were recorded.

RESULTS

The mean ages of the micro-PERC and RIRS groups were 4 ± 2.3 and 10.9 ± 3 years, respectively (p = 0.001). However, the mean stone sizes were 12.2 ± 2.8 and 13.7 ± 3.5 mm, respectively (p > 0.05). The mean duration of operation was 75.1 ± 18.9 min in the micro-PERC group and 62.3 ± 15.3 min in the RIRS group (p > 0.05). In addition, the mean duration of fluoroscopy was 115 ± 35.4 s in the micro-PERC group and 39.9 ± 15.3 s in the RIRS group. The stone-free rates in the micro-PERC and RIRS groups following the procedure were reported to be 84% (21/25) and 82.6% (19/23), respectively (p > 0.05). In terms of the degree of preoperative hydronephrosis between the groups, the rates of mild and moderate-severe disease were 76% (19 out of 25) and 24% (6 out of 25), and 69.5% (16 out of 23) and 30.4% (7 out of 23) in the micro-PERC and RIRS groups, respectively.

CONCLUSION

In recent years, technological developments in minimally invasive procedures, such as micro-PERC and RIRS, have facilitated choices made by urologists in the effective and safe first-line treatment in pediatric patients.

摘要

简介

随着内镜手术的进步,泌尿系统结石的开放性手术为儿童肾结石疾病患者应用微创治疗方法开辟了道路。这些治疗选择包括体外冲击波碎石术(ESWL)、经皮肾镜取石术(PCNL)和逆行性肾内手术(RIRS)。

目的

我们旨在比较 RIRS 和微 PCNL 技术在儿童肾结石患者手术治疗中的疗效和安全性。

研究设计

回顾性分析了 48 名接受 RIRS 或微 PERC 治疗儿童肾结石病的儿科患者。在手术前评估了尿液分析、尿液培养、血清肌酐(Cr)、血尿素氮(BUN)、钙、磷、甲状旁腺激素、24 小时尿液样本、全血细胞计数(CBC)、泌尿系统 X 线、肾脏输尿管膀胱(KUB)和泌尿系统超声检查结果。如果需要,还进行了静脉肾盂造影(IVP)、非增强计算机断层扫描(CT)和肾闪烁扫描评估。患者分为两组:微 PERC 组(n=25)和 RIRS 组(n=23)。记录了手术持续时间、透视时间、住院时间、并发症发生率和结石清除率等数据。

结果

微 PERC 组和 RIRS 组的平均年龄分别为 4±2.3 岁和 10.9±3 岁(p=0.001)。然而,平均结石大小分别为 12.2±2.8 毫米和 13.7±3.5 毫米(p>0.05)。微 PERC 组的手术持续时间为 75.1±18.9 分钟,RIRS 组为 62.3±15.3 分钟(p>0.05)。此外,微 PERC 组的透视时间为 115±35.4 秒,RIRS 组为 39.9±15.3 秒。微 PERC 组和 RIRS 组术后结石清除率分别为 84%(21/25)和 82.6%(19/23)(p>0.05)。在两组术前肾积水程度方面,轻度和中度重度疾病的发生率分别为 76%(19/25)和 24%(6/25),微 PERC 组和 RIRS 组分别为 69.5%(16/23)和 30.4%(7/23)。

结论

近年来,微创技术的发展,如微 PERC 和 RIRS,为泌尿科医生在儿童患者的有效和安全一线治疗中提供了更多选择。

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