Kim Sung-Woo, Lee Yong-Hoon, Lee Sang-Rae, Kim Kyoung-Min, Lee Young-Jeon, Jung Kang-Jin, Chang Kwon-Sik, Kim Doo, Son Hwa-Young, Reu Dong-Suck, Chang Kyu-Tae
The National Primate Research Center, Korea Research Institute of Bioscience and Biotechnology, Ochang, Cheongwon, Chungbuk 363-883, Republic of Korea.
J Vet Med Sci. 2012 Sep;74(9):1229-32. doi: 10.1292/jvms.11-0354. Epub 2012 May 21.
Ovarian cyst is common incidental finding in humans and many animals and includes follicular cysts, cystic rete ovarii and mesonephric duct cysts. Ovarian cyst is often associated with reproductive disorders in humans and animals. We found accidentally bilateral cystic masses in ovaries in an African green monkey. Grossly, the left and right ovarian cystic masses were single unilocular cystic structures measuring 0.6 and 1.8 cm in diameter, respectively. Histologically, both cysts were thin-walled structures that arose from the center of the ovary and displaced ovarian tissue peripherally. The cysts were lined by a single layer of nonciliated low cuboidal epithelium. Immunohistochemically, epithelial cells in the cysts were positive for cytokeratin, and the stromal cells were positive for smooth muscle actin but negative for vimentin. These results suggest that these ovarian cysts in an African green monkey are cystic rete ovarii. To our knowledge, this is the first report of cystic rete ovarii in African green monkeys and may be of value in relation to research of the pathogenesis and treatment of ovarian cyst.
卵巢囊肿在人类和许多动物中是常见的偶然发现，包括卵泡囊肿、卵巢网囊肿和中肾管囊肿。卵巢囊肿常与人类和动物的生殖紊乱有关。我们在一只非洲绿猴的卵巢中意外发现双侧囊性肿物。大体上，左右卵巢囊性肿物均为单个单房囊性结构，直径分别为0.6厘米和1.8厘米。组织学上，两个囊肿均为薄壁结构，起源于卵巢中心并将卵巢组织挤压至周边。囊肿内衬单层无纤毛的低立方上皮。免疫组化显示，囊肿内的上皮细胞细胞角蛋白阳性，间质细胞平滑肌肌动蛋白阳性但波形蛋白阴性。这些结果表明，这只非洲绿猴的这些卵巢囊肿为卵巢网囊肿。据我们所知，这是非洲绿猴卵巢网囊肿的首次报道，可能对卵巢囊肿的发病机制和治疗研究具有价值。
