Departamento de Clínica e Cirurgia Veterinárias, Escola de Veterinária, Universidade Federal de Minas Gerais, Minas Gerais, Brasil.
BMC Vet Res. 2012 Dec 5;8:235. doi: 10.1186/1746-6148-8-235.
Stratified keratinizing squamous epithelium in the ovary has been associated with the diagnosis of ovarian teratoma in cows. Recently, the diagnosis of "epidermoid cyst" has been proposed. A case of squamous metaplasia of the rete ovarii in a Zebu cow is described in this report.
A crossbreed Zebu cow had both ovaries enlarged with multiple cysts. Most cysts were lined by well differentiated keratinizing stratified squamous epithelium and filled with keratinized lamellar material. Some cysts were lined by an epithelial layer that ranged from single cuboidal, double cuboidal epithelium, stratified non keratinized epithelium, and areas of keratinizing stratified squamous epithelium. Single or double layered cuboidal epithelia of the cysts expressed low molecular weight cytokeratin 7, whose expression was absent in the keratinizing stratified squamous epithelia of same cysts. Conversely, high molecular weight cytokeratins 1, 5, 10, and 14 were strongly expressed by the keratinizing stratified epithelium.
Squamous metaplasia of the rete ovarii was diagnosed. Squamous metaplasia of the rete ovarii, may account for some of the previously described squamous lesions in the ovary, which may have been misinterpreted as teratoma or epidermoid cysts.
卵巢中分层角化的鳞状上皮与牛卵巢畸胎瘤的诊断有关。最近，提出了“表皮样囊肿”的诊断。本文报道了一例努比亚奶牛卵巢网腔的鳞状化生。
杂交努比亚奶牛的两个卵巢均增大，伴有多个囊肿。大多数囊肿由分化良好的角化分层鳞状上皮衬里，并充满角化的板层物质。一些囊肿衬有上皮层，范围从单层立方上皮、双层立方上皮、非角化分层上皮和角化分层鳞状上皮区域。囊肿的单层或双层立方上皮表达低分子量细胞角蛋白 7，而同一囊肿的角化分层鳞状上皮中则没有表达。相反，高分子量细胞角蛋白 1、5、10 和 14 在角化分层上皮中强烈表达。
诊断为卵巢网腔的鳞状化生。卵巢网腔的鳞状化生可能是以前描述的卵巢中一些鳞状病变的原因，这些病变可能被误诊为畸胎瘤或表皮样囊肿。
