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从患有急性青草搐搦的马血清中分离出的化合物的特性分析

Characterisation of compounds isolated from the sera of horses with acute grass sickness.

作者信息

Pemberton A D, Hodgson J C, Gilmour J S, Doxey D L

机构信息

Moredun Research Institute, Edinburgh.

出版信息

Res Vet Sci. 1990 Nov;49(3):315-8.

PMID:2267422
Abstract

Isolates were prepared from the sera of 12 horses with acute grass sickness, using methods reported to yield serum fractions associated with neurotoxicity, and their components identified by liquid chromatography and spectroscopy. All isolates were found to contain cortisol and six isolates also contained a degradation product of an analgesic drug, dipyrone. However, no recognised neurotoxin was detected.

摘要

从12匹患有急性青草搐搦症的马的血清中分离出样本,采用据报道可产生与神经毒性相关血清成分的方法,并通过液相色谱和光谱法鉴定其成分。所有分离物均被发现含有皮质醇,6个分离物还含有一种镇痛药安乃近的降解产物。然而,未检测到公认的神经毒素。

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