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明亮早晨光线对睡眠时相延迟综合征的治疗中的相移效应

Phase-shifting effects of bright morning light as treatment for delayed sleep phase syndrome.

作者信息

Rosenthal N E, Joseph-Vanderpool J R, Levendosky A A, Johnston S H, Allen R, Kelly K A, Souetre E, Schultz P M, Starz K E

机构信息

Clinical Psychobiology Branch, National Institute of Mental Health, Bethesda, Maryland 20892.

出版信息

Sleep. 1990 Aug;13(4):354-61.

PMID:2267478
Abstract

Bright light has recently been shown to have phase-shifting effects on human circadian rhythms. In this study we applied this effect to 20 patients with delayed sleep phase syndrome (DSPS) who were unable to fall asleep at conventional clock times and had a problem staying alert in the morning. In a controlled treatment study, we found that 2 h of bright light exposure in the morning together with light restriction in the evening successfully phase advanced circadian rhythms of core body temperature and multiple sleep latencies in these patients. This finding corroborates the importance of light for entraining human circadian rhythms.

摘要

近期研究表明,强光对人体昼夜节律具有相位转移效应。在本研究中,我们将此效应应用于20例睡眠相位后移综合征(DSPS)患者,这些患者无法在常规时钟时间入睡,且早晨难以保持清醒。在一项对照治疗研究中,我们发现,早晨2小时的强光照射以及晚上的光线限制成功地使这些患者的核心体温昼夜节律和多次睡眠潜伏期提前。这一发现证实了光线对调节人体昼夜节律的重要性。

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