Cuevas Pedro, Angulo Javier, Giménez-Gallego Guillermo
Research Department, Hospital Ramon y Cajal, Madrid, Spain.
BMJ Case Rep. 2011 Oct 16;2011:bcr0820114579. doi: 10.1136/bcr.08.2011.4579.
This case report is a representative example from a study directed to assess the long-term clinical benefit of dobesilate in rosacea in five enrolled papulopustular rosacea patients with several years of disease, treated topically with 5% potassium dobesilate cream for 3 weeks. The patient suffered papulopustular rosacea for more than 10 years, during which she received topical metronidazole and azelaic acid, and systemic doxycycline therapies without satisfactory improvement. Dobesilate treatment promoted improvement of rosacea symptoms and signs. Two years after treatment the patient still shows a good facial cosmesis.
本病例报告是一项研究的典型案例，该研究旨在评估羟苯磺酸对5例已患数年丘疹脓疱型酒渣鼻患者的长期临床疗效，这些患者局部外用5%羟苯磺酸乳膏治疗3周。该患者患丘疹脓疱型酒渣鼻超过10年，在此期间，她接受过局部甲硝唑和壬二酸治疗以及口服多西环素治疗，但均未获得满意疗效。羟苯磺酸治疗促使酒渣鼻症状和体征得到改善。治疗两年后，该患者面部外观依然良好。
