Dixon Luke, Diaz-Cano Salvador, Schulte Klaus-Martin
Department of General Surgery, King's College Hospital, King's Health Partners, London, UK.
BMJ Case Rep. 2011 Oct 28;2011:bcr0720114516. doi: 10.1136/bcr.07.2011.4516.
A 34-year-old woman with papillary thyroid carcinoma underwent total thyroidectomy with central and lateral lymphadenectomy. Immediate airway compromise required re-intubation immediately after surgery. Marked tracheal and bronchial collapse of greater than 50% of the lumen indicated tracheobronchomalacia. Subsequent attempts at extubation failed over the next week. The patient soon developed evidence of a lower respiratory tract infection. Empirical treatment with penicillins was unsuccessful. A clinical suspicion of chlamydia infection prompted initiation of macrolide treatment followed by resolution of both the patient's respiratory infection and tracheobronchomalacia. Serology returned positive for Chlamydophila psittaci infection. It later transpired that the patient had symptoms of an upper respiratory tract infection just prior to surgery. This case demonstrates an interesting and unreported cause of tracheobronchomalacia as well as providing a good lesson on the importance of preoperative screening for infection.
一名34岁的甲状腺乳头状癌女性患者接受了全甲状腺切除术及中央区和侧方淋巴结清扫术。术后立即出现气道受压,需要立即重新插管。气管和支气管明显塌陷,管腔狭窄超过50%,提示气管支气管软化症。在接下来的一周内,随后的拔管尝试均失败。患者很快出现下呼吸道感染的迹象。使用青霉素进行经验性治疗未成功。临床怀疑衣原体感染促使开始使用大环内酯类药物治疗,随后患者的呼吸道感染和气管支气管软化症均得到缓解。血清学检测显示鹦鹉热衣原体感染呈阳性。后来发现该患者在手术前有上呼吸道感染症状。该病例展示了气管支气管软化症一个有趣且未被报道的病因,同时也为术前感染筛查的重要性提供了一个很好的教训。