Faculty of Psychology and Educational Sciences, University of Coimbra, Coimbra, Portugal.
J Int Neuropsychol Soc. 2012 Nov;18(6):1031-40. doi: 10.1017/S135561771200077X. Epub 2012 Jun 8.
The Montreal Cognitive Assessment (MoCA) is a brief instrument developed for the screening of milder forms of cognitive impairment, having surpassed the well-known limitations of the MMSE. The aim of the present study was to validate the MoCA as well as its short version, which was proposed by the NINDS-CSN VCI Harmonization Standards for screening Vascular Dementia (VaD) patients. The results, based on a homogeneous sample of 34 VaD patients, indicate that the MoCA is a psychometrically valid and reliable instrument for cognitive screening in VaD patients, showing excellent discriminant validity. Both the full and short versions of the MoCA had excellent diagnostic accuracy in discriminating VaD patients, exhibiting an area under curve (AUC) higher than the MMSE [AUC(MoCA full version) = .950; 95% IC = .868-.988; AUC(MoCA short version) = .936; 95% IC = .849-.981; AUC(MMSE) = .860; 95% IC = .754-.932]. With a cutoff below 17 on the MoCA full version and 8 on the short version, the results for sensitivity, specificity, positive and negative predictive values, and classification accuracy were superior compared to the MMSE. In conclusion, both versions of the MoCA are valid, reliable, sensitive and accurate screening instruments for VaD patients.
蒙特利尔认知评估（MoCA）是一种专为轻度认知障碍筛选而开发的简短工具，它克服了 MMSE 众所周知的局限性。本研究旨在验证 MoCA 及其简短版本，该版本由 NINDS-CSN VCI 血管性痴呆（VaD）患者筛查的协调标准提出。基于 34 名 VaD 患者的同质样本的结果表明，MoCA 是一种用于 VaD 患者认知筛查的心理测量有效且可靠的工具，具有出色的判别效度。MoCA 的完整版本和简短版本在区分 VaD 患者方面均具有出色的诊断准确性，其曲线下面积（AUC）高于 MMSE [AUC（MoCA 完整版本）=.950；95%置信区间（CI）=.868-.988；AUC（MoCA 简短版本）=.936；95%CI =.849-.981；AUC（MMSE）=.860；95%CI =.754-.932]。MoCA 完整版本的得分低于 17 分，简短版本的得分低于 8 分，其敏感性、特异性、阳性和阴性预测值以及分类准确性的结果均优于 MMSE。总之，MoCA 的两个版本都是 VaD 患者有效、可靠、敏感和准确的筛查工具。
