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耳廓皮脂腺瘤

Sebaceoma of the auricle.

作者信息

Jacobson J P, Weisstuch A, Hajdu C, Myssiorek D

机构信息

Department of Otolaryngology-Head and Neck Surgery, NYU Langone Medical Center, NY, USA.

出版信息

J Laryngol Otol. 2012 Aug;126(8):830-2. doi: 10.1017/S0022215112000874. Epub 2012 Jun 8.

Abstract

OBJECTIVE

To report a case of sebaceoma of the auricle, and to discuss the differential diagnosis, histopathological features, surgical management and genetic associations of this entity.

METHODS

Case report and review of the medical literature.

RESULTS

A 79-year-old man presented with a slowly growing lesion of his auricle. Excision of the mass and histopathological review revealed a benign, basaloid, adnexal neoplasm consistent with sebaceoma. Due to its association with Muir-Torre syndrome and increased risk of visceral malignancy, the patient was followed closely for signs of malignancy. At 36 months post-excision, there were no signs of recurrence; thereafter, the patient continued to receive routine cancer surveillance follow up.

CONCLUSION

Sebaceoma is a rarely encountered, benign, adnexal neoplasm which can occur in the head and neck. The treatment is surgical excision, and recurrence is rare. Sebaceoma can occur as part of Muir-Torre syndrome, and in these patients there is an increased risk of other sebaceous lesions and visceral malignancy; thus, genetic testing and surveillance should be strongly considered.

摘要

目的

报告1例耳廓皮脂腺瘤病例,并探讨该疾病的鉴别诊断、组织病理学特征、手术治疗及遗传学关联。

方法

病例报告及医学文献回顾。

结果

1名79岁男性患者耳廓出现缓慢生长的肿物。肿物切除及组织病理学检查显示为符合皮脂腺瘤的良性基底样附属器肿瘤。鉴于其与穆尔-托里综合征相关且内脏恶性肿瘤风险增加,对该患者进行密切随访以观察有无恶性肿瘤迹象。切除术后36个月,无复发迹象;此后,患者继续接受常规癌症监测随访。

结论

皮脂腺瘤是一种罕见的良性附属器肿瘤,可发生于头颈部。治疗方法为手术切除,复发罕见。皮脂腺瘤可作为穆尔-托里综合征的一部分出现,此类患者发生其他皮脂腺病变及内脏恶性肿瘤的风险增加;因此,应强烈考虑进行基因检测及监测。

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