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妊娠期自发性肾上腺出血

Spontaneous adrenal haemorrhage in pregnancy.

作者信息

Anagnostopoulos A, Sharma S

机构信息

Obstetrics and Gynaecology Department, Liverpool Women's Hospital, Liverpool, UK.

出版信息

BMJ Case Rep. 2011 Sep 13;2011:bcr0720114496. doi: 10.1136/bcr.07.2011.4496.

Abstract

The authors present a case of spontaneous adrenal haemorrhage, in a 28-year-old woman at 36 weeks of a twin pregnancy. Initial symptom was sudden onset chest pain which soon migrated to abdomen, accompanied by hypovolaemic shock and fetal bradycardia. Subsequent caesarean section for suspected placental abruption and resuscitation with nine units of blood, 10 of cryoprecipitate, four of fresh frozen plasma and two of platelets, in order to treat anaemia of Hgb of 3.6 g/dl and disseminated intravascular coagulation, failed to stabilise the woman. A CT scan of abdomen and pelvis then revealed a 15×17×17 cm retroperitoneal haematoma, secondary to right adrenal haemorrhage. Management was with laparotomy drainage and packing of the retroperitoneal haematoma along with the use of activated factor VII. Adrenal haemorrhage in pregnancy is an extremely rare, acute, life-threatening condition, presenting with non-specific symptoms.

摘要

作者报告了一例双胎妊娠36周的28岁女性自发性肾上腺出血病例。最初症状为突发胸痛,随后很快转移至腹部,伴有低血容量性休克和胎儿心动过缓。因怀疑胎盘早剥行剖宫产,并输注9单位全血、10单位冷沉淀、4单位新鲜冰冻血浆和2单位血小板进行复苏,以治疗血红蛋白为3.6 g/dl的贫血和弥散性血管内凝血,但该女性病情未能稳定。随后腹部和盆腔CT扫描显示,右肾上腺出血继发15×17×17 cm腹膜后血肿。治疗方法为剖腹探查引流并填塞腹膜后血肿,同时使用活化凝血因子VII。妊娠期肾上腺出血是一种极其罕见、急性且危及生命的疾病,症状不具有特异性。

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