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本文引用的文献

1
Serious injuries from dishwasher powder ingestions in small children.幼儿因误食洗碗机粉而受重伤。
J Paediatr Child Health. 2006 Mar;42(3):129-33. doi: 10.1111/j.1440-1754.2006.00811.x.
2
Sanichlor-induced atopic dermatitis and asthma in ophthalmologists.眼科医生中三氯生诱发的特应性皮炎和哮喘。
Eye (Lond). 2003 Jan;17(1):108-9. doi: 10.1038/sj.eye.6700228.
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Risk in cleaning: chemical and physical exposure.清洁中的风险:化学和物理暴露。
Sci Total Environ. 1998 Apr 23;215(1-2):135-56. doi: 10.1016/s0048-9697(98)00110-7.
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A rapid dosimetric method with controlled tidal breathing for histamine challenge. Repeatability and distribution of bronchial reactivity in a clinical material.一种用于组胺激发试验的、在控制潮式呼吸情况下的快速剂量测定方法。临床材料中支气管反应性的可重复性和分布情况。
Chest. 1993 Jul;104(1):164-70. doi: 10.1378/chest.104.1.164.
5
Reactive airways dysfunction syndrome (RADS). Persistent asthma syndrome after high level irritant exposures.反应性气道功能障碍综合征(RADS)。高浓度刺激性物质暴露后出现的持续性哮喘综合征。
Chest. 1985 Sep;88(3):376-84. doi: 10.1378/chest.88.3.376.

急性吸入洗碗机用洗涤剂粉末致反应性呼吸道功能障碍综合征。

Reactive airways dysfunction syndrome from acute inhalation of a dishwasher detergent powder.

机构信息

Finnish Institute of Occupational Health, Occupational Medicine, Helsinki, Finland.

出版信息

Can Respir J. 2012 May-Jun;19(3):e25-8. doi: 10.1155/2012/150919.

DOI:10.1155/2012/150919
PMID:22679618
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3418100/
Abstract

Reactive airway dysfunction syndrome, a type of occupational asthma without a latency period, is induced by irritating vapour, fumes or smoke. The present report is the first to describe a case of reactive airway dysfunction syndrome caused by acute exposure to dishwater detergent containing sodium metasilicate and sodium dichloroisocyanurate. The diagnosis was based on exposure data, clinical symptoms and signs, as well as respiratory function tests. A 43-year-old nonatopic male apprentice cook developed respiratory symptoms immediately after exposure to a cloud of detergent powder that was made airborne by vigorous shaking of the package. In spirometry, combined obstructive and restrictive ventilatory impairment developed, and the histamine challenge test revealed bronchial hyper-responsiveness. Even routine handling of a strongly caustic detergent, such as filling a dishwasher container, is not entirely risk free and should be performed with caution.

摘要

气道反应性障碍综合征,一种无潜伏期的职业性哮喘,是由刺激性蒸气、烟雾或烟尘引起的。本报告首次描述了一例由急性接触含偏硅酸钠和二氯异氰尿酸钠的洗碗液引起的气道反应性障碍综合征。诊断基于暴露数据、临床症状和体征以及呼吸功能测试。一名 43 岁的非过敏男性学徒厨师在剧烈摇晃包装后,吸入了一团清洁剂粉末,立即出现呼吸道症状。在肺量测定中,出现混合性阻塞和限制性通气障碍,组胺挑战测试显示支气管高反应性。即使是常规处理强腐蚀性清洁剂,如洗碗机容器的填充,也并非完全没有风险,应谨慎操作。