Division of Nephrology, Ege University School of Medicine, Izmir, Turkey.
Ren Fail. 2012;34(7):876-9. doi: 10.3109/0886022X.2012.690805. Epub 2012 Jun 8.
Gastrointestinal complications are common in renal transplant recipients and may arise from any part of the gastrointestinal tract. Irritable bowel syndrome (IBS) is highly common in the general population, but the status is not known in renal transplant patients. In this study, we evaluated the prevalence of IBS and its association with health-related quality of life (HRQOL), anxiety, and depression in renal transplant patients.
One hundred and ninety-eight patients were enrolled in this study. Sociodemographic and laboratory variables were recorded. Severity of depressive and anxiety symptoms and HRQOL were assessed by the Beck Depression Inventory, State-Trait Anxiety Inventory, and Short Form 36 (SF-36), respectively. Diagnosis of IBS was based on Rome III criteria.
The mean age was 38 ± 10 years and 61% were male. The mean transplant duration was 62 ± 54 months. Among 198 patients, 55 (27%) had IBS. Patients with IBS had lower SF-36 scores and had higher depressive and anxiety symptoms than patients without IBS.
IBS is highly prevalent in renal transplant patients. The presence of IBS is closely related with HRQOL anxiety and depression.
胃肠道并发症在肾移植受者中很常见，可能发生在胃肠道的任何部位。肠易激综合征（IBS）在普通人群中非常常见，但在肾移植患者中的情况尚不清楚。在这项研究中，我们评估了 IBS 的患病率及其与肾移植患者的健康相关生活质量（HRQOL）、焦虑和抑郁的关系。
本研究纳入了 198 名患者。记录了社会人口统计学和实验室变量。使用贝克抑郁量表、状态-特质焦虑量表和 36 项简短健康调查问卷（SF-36）分别评估抑郁和焦虑症状的严重程度以及 HRQOL。根据罗马 III 标准诊断 IBS。
患者的平均年龄为 38 ± 10 岁，61%为男性。平均移植时间为 62 ± 54 个月。在 198 名患者中，55 名（27%）患有 IBS。与无 IBS 的患者相比，患有 IBS 的患者的 SF-36 评分较低，且抑郁和焦虑症状更严重。
IBS 在肾移植患者中患病率很高。IBS 的存在与 HRQOL、焦虑和抑郁密切相关。
