Department of Neurosciences, University of California, San Diego, La Jolla, CA 92093-0662, USA.
Neuron. 2012 Jun 7;74(5):777-91. doi: 10.1016/j.neuron.2012.05.006.
Progress in the field of axonal regeneration research has been like the process of axonal growth itself: there is steady progress toward reaching the target, but there are episodes of mistargeting, misguidance along false routes, and connections that must later be withdrawn. This primer will address issues in the study of axonal growth after central nervous system injury in an attempt to provide guidance toward the goal of progress in the field. We address definitions of axonal growth, sprouting and regeneration after injury, and the research tools to assess growth.
朝着目标稳步前进，但也会出现靶向错误、沿着错误路线误导、以及后来必须撤回的连接等情况。本入门将探讨中枢神经系统损伤后轴突生长研究中的问题，试图为该领域的进展提供指导。我们讨论了轴突生长、损伤后发芽和再生的定义，以及评估生长的研究工具。
