Service de neurologie, centre de référence atrophie multisystématisée, centre de reference AMS, hôpital du Haut-Lévêque, CHU de Bordeaux, avenue Magellan, 33604 Pessac cedex, France.
Rev Neurol (Paris). 2013 Jan;169(1):53-8. doi: 10.1016/j.neurol.2012.02.011. Epub 2012 Jun 6.
Multiple system atrophy (MSA) has considerable impact on health-related quality of life. The MSA health-related Quality of Life scale (MSA-QoL) is a patient-reported questionnaire, which has been recently designed to evaluate the quality of life in MSA. The objective of the present study was to validate the French version of the MSA-QoL questionnaire.
One hundred and thirty-six consecutive MSA patients were included in the study. Four patients with more than 10% missing responses were excluded from the final analysis. Data quality, scaling assumptions, acceptability, reliability and validity were assessed similar to the original validation of the English version.
Missing responses were low, item and subscale scores were evenly distributed and floor and ceiling effects were negligible. Item-total correlations were higher than the recommended greater than 0.30 and internal consistency was high for all subscales. Test-retest reliability was good for all subscales. Validity was supported by moderate interscale correlations between the subscales and the predicted correlations with other scales assessing motor disability, activities of daily living, quality of life and mood.
The French version of the MSA-QoL displays robust psychometric properties similar to the English version.
The French version of MSA-QoL seems suitable for assessing quality of life in French speaking MSA patients.
多系统萎缩（MSA）对健康相关生活质量有很大影响。MSA 健康相关生活质量量表（MSA-QoL）是一种患者报告的问卷，最近设计用于评估 MSA 的生活质量。本研究的目的是验证 MSA-QoL 问卷的法语版本。
本研究纳入了 136 例连续 MSA 患者。有 4 名患者因超过 10%的缺失应答而被排除在最终分析之外。数据质量、定标假设、可接受性、可靠性和有效性评估与英语版本的原始验证相似。
缺失应答率较低，项目和子量表得分分布均匀，地板效应和天花板效应可忽略不计。项目-总分相关性高于建议的大于 0.30，所有子量表的内部一致性均较高。所有子量表的重测信度均良好。子量表之间的中等相关性以及与评估运动障碍、日常生活活动、生活质量和情绪的其他量表的预测相关性支持了有效性。
MSA-QoL 的法语版本具有与英语版本相似的可靠心理测量学特性。
MSA-QoL 的法语版本似乎适合评估讲法语的 MSA 患者的生活质量。
