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胚胎选择方法的进展。

Advances in embryo selection methods.

作者信息

Ajduk Anna, Zernicka-Goetz Magdalena

出版信息

F1000 Biol Rep. 2012;4:11. doi: 10.3410/B4-11. Epub 2012 Jun 1.

Abstract

Despite many recent advances in the field of reproductive biology and medicine, the efficiency of in vitro fertilization procedures remains relatively low. There is a need for a reliable and non-invasive method of embryo selection to ensure that only embryos with the highest developmental potential are chosen for transfer to mothers-to-be. Here, we compare various methods currently used for assessing embryonic viability, such as examination of embryonic morphology, quality of the genetic material, or metabolism. Additionally, we discuss novel procedures for embryonic assessment based on advanced time-lapse imaging techniques, which show great promise and may lead to increased in vitro fertilization efficiencies.

摘要

尽管生殖生物学和医学领域最近取得了许多进展,但体外受精程序的效率仍然相对较低。需要一种可靠且非侵入性的胚胎选择方法,以确保仅选择具有最高发育潜力的胚胎移植给准母亲。在此,我们比较了目前用于评估胚胎活力的各种方法,例如胚胎形态检查、遗传物质质量或代谢情况。此外,我们还讨论了基于先进延时成像技术的胚胎评估新程序,这些技术显示出巨大的前景,可能会提高体外受精效率。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/1744/3369238/389417b472e9/biolrep-04-11-g001.jpg

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