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物质使用与轻度创伤性脑损伤的风险降低及预防:一种新型治疗模式

Substance use and mild traumatic brain injury risk reduction and prevention: a novel model for treatment.

作者信息

Olson-Madden Jennifer H, Brenner Lisa A, Corrigan John D, Emrick Chad D, Britton Peter C

机构信息

Mental Illness Research, Education, and Clinical Center (MIRECC), Eastern Colorado Health Care System (ECHCS) Veterans Affairs Medical Center, Denver, CO 80220, USA.

出版信息

Rehabil Res Pract. 2012;2012:174579. doi: 10.1155/2012/174579. Epub 2012 May 17.

Abstract

Traumatic brain injury (TBI) and substance use disorders (SUDs) frequently co-occur. Individuals with histories of alcohol or other drug use are at greater risk for sustaining TBI, and individuals with TBI frequently misuse substances before and after injury. Further, a growing body of literature supports the relationship between comorbid histories of mild TBI (mTBI) and SUDs and negative outcomes. Alcohol and other drug use are strongly associated with risk taking. Disinhibition, impaired executive function, and/or impulsivity as a result of mTBI also contribute to an individual's proclivity towards risk-taking. Risk-taking behavior may therefore, be a direct result of SUD and/or history of mTBI, and risky behaviors may predispose individuals for subsequent injury or continued use of substances. Based on these findings, evaluation of risk-taking behavior associated with the co-occurrence of SUD and mTBI should be a standard clinical practice. Interventions aimed at reducing risky behavior among members of this population may assist in decreasing negative outcomes. A novel intervention (Substance Use and Traumatic Brain Injury Risk Reduction and Prevention (STRRP)) for reducing and preventing risky behaviors among individuals with co-occurring mTBI and SUD is presented. Areas for further research are discussed.

摘要

创伤性脑损伤(TBI)与物质使用障碍(SUDs)经常同时出现。有酒精或其他药物使用史的个体遭受TBI的风险更高,而患有TBI的个体在受伤前后经常滥用物质。此外,越来越多的文献支持轻度创伤性脑损伤(mTBI)和物质使用障碍的共病病史与不良后果之间的关系。酒精和其他药物使用与冒险行为密切相关。mTBI导致的去抑制、执行功能受损和/或冲动也会促使个体倾向于冒险。因此,冒险行为可能是物质使用障碍和/或mTBI病史的直接结果,而冒险行为可能使个体更容易遭受后续伤害或持续使用物质。基于这些发现,评估与物质使用障碍和mTBI共病相关的冒险行为应成为标准的临床实践。旨在减少该人群中冒险行为的干预措施可能有助于减少不良后果。本文介绍了一种用于减少和预防同时患有mTBI和物质使用障碍的个体冒险行为的新型干预措施(物质使用与创伤性脑损伤风险降低与预防(STRRP))。还讨论了进一步研究的领域。

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