Department of Paediatrics Community Health Sciences, Faculty of Medicine, University of Calgary, Calgary, Alberta, Canada.
Paediatr Perinat Epidemiol. 2012 Jul;26(4):316-27. doi: 10.1111/j.1365-3016.2012.01286.x. Epub 2012 May 9.
Post-partum depression (PPD) is the most common complication of pregnancy in developed countries, affecting 10-15% of new mothers. There has been a shift in thinking less in terms of PPD per se to a broader consideration of poor mental health, including anxiety after giving birth. Some risk factors for poor mental health in the post-partum period can be identified prenatally; however prenatal screening tools developed to date have had poor sensitivity and specificity. The objective of this study was to develop a screening tool that identifies women at risk of distress, operationalized by elevated symptoms of depression and anxiety in the post-partum period using information collected in the prenatal period.
Using data from the All Our Babies Study, a prospective cohort study of pregnant women living in Calgary, Alberta (N = 1578), we developed an integer score-based prediction rule for the prevalence of PPD, as defined as scoring 10 or higher on the Edinburgh Postnatal Depression Scale (EPDS) at 4-months postpartum.
The best fit model included known risk factors for PPD: depression and stress in late pregnancy, history of abuse, and poor relationship quality with partner. Comparison of the screening tool with the EPDS in late pregnancy showed that our tool had significantly better performance for sensitivity. Further validation of our tool was seen in its utility for identifying elevated symptoms of postpartum anxiety.
This research heeds the call for further development and validation work using psychosocial factors identified prenatally for identifying poor mental health in the post-partum period.
产后抑郁症(PPD)是发达国家妊娠最常见的并发症,影响 10-15%的新妈妈。人们的思维方式已经从单纯的产后抑郁症本身转变为更广泛地考虑心理健康不良,包括产后焦虑。一些产后心理健康不良的风险因素可以在产前识别;然而,迄今为止开发的产前筛查工具的敏感性和特异性都很差。本研究的目的是开发一种筛查工具,通过在产前收集的信息,识别出有抑郁和焦虑症状的高危产妇。
本研究使用了来自卡尔加里的前瞻性队列研究(All Our Babies 研究)的数据,该研究纳入了 1578 名孕妇,我们开发了一种基于整数评分的预测规则,用于预测产后抑郁的患病率,定义为产后 4 个月时爱丁堡产后抑郁量表(EPDS)评分达到 10 分或更高。
最佳拟合模型纳入了产后抑郁的已知风险因素:孕晚期抑郁和压力、虐待史和与伴侣的关系质量差。与孕晚期的 EPDS 相比,该筛查工具的敏感性表现出更好的性能。该工具在识别产后焦虑的症状方面的有效性也得到了进一步验证。
本研究响应了进一步开发和验证使用产前确定的心理社会因素来识别产后心理健康不良的呼吁。