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免疫功能正常宿主中首例有记录的都柏林念珠菌性软脑膜疾病病例。

The first documented case of Candida dubliniensis leptomeningeal disease in an immunocompetent host.

作者信息

Andrew Nicholas H, Ruberu Ravi P, Gabb Genevieve

机构信息

Department of Medicine, Royal Adelaide Hospital, Adelaide, South Australia, Australia.

出版信息

BMJ Case Rep. 2011 Aug 4;2011:bcr0620114384. doi: 10.1136/bcr.06.2011.4384.

Abstract

In June 2008, a 25-year-old man presented to the Royal Adelaide Hospital, Australia, with Candida dubliniensis leptomeningeal disease. On examination the patient had focal neurological deficits, both sensory and motor. He tested negative for HIV and had normal T cell subsets. The patient was treated with 6 weeks of intravenous liposomal amphotericin B and oral flucytosine, and had a full recovery.

摘要

2008年6月,一名25岁男性因都柏林念珠菌性软脑膜疾病就诊于澳大利亚阿德莱德皇家医院。检查发现该患者存在感觉和运动方面的局灶性神经功能缺损。他的HIV检测呈阴性,T细胞亚群正常。该患者接受了为期6周的静脉注射脂质体两性霉素B和口服氟胞嘧啶治疗,最终完全康复。

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