无金属和化学氧化剂条件下的芳香化合物的 C-H/C-H 交叉偶联：自由基阳离子池的应用。
Metal- and chemical-oxidant-free C-H/C-H cross-coupling of aromatic compounds: the use of radical-cation pools.
机构信息
Department of Synthetic Chemistry and Biological Chemistry, Graduate School of Engineering, Kyoto University, Nishikyo-ku, Kyoto 615-8510, Japan.
出版信息
Angew Chem Int Ed Engl. 2012 Jul 16;51(29):7259-62. doi: 10.1002/anie.201202788. Epub 2012 Jun 11.
Pool and couple: A method for oxidative C-H/C-H cross-coupling has been developed using "radical-cation pools". Aromatic compounds react with aryl radical cations, which are generated and accumulated by low-temperature electrolysis (see scheme). This method avoids both the nonselective oxidation of substrates and oxidation of products and effects the C-H/C-H cross-coupling of aromatic compounds without metal complexes and chemical oxidants.
池偶法
一种利用“自由基阳离子池”进行氧化 C-H/C-H 交叉偶联的方法已经被开发出来。芳香族化合物与芳基自由基阳离子反应，后者通过低温电解生成并积累（见方案）。该方法避免了底物的非选择性氧化和产物的氧化，实现了无需金属配合物和化学氧化剂的芳香族化合物的 C-H/C-H 交叉偶联。
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