Gladstone Institute of Neurological Disease, University of California, San Francisco, California, USA.
Physiology (Bethesda). 2012 Jun;27(3):167-77. doi: 10.1152/physiol.00004.2012.
Direct and indirect pathway striatal neurons are known to exert opposing control over motor output. In this review, we discuss a hypothetical extension of this framework, in which direct pathway striatal neurons also mediate reinforcement and reward, and indirect pathway neurons mediate punishment and aversion.
已知直接和间接通路纹状体神经元对运动输出施加相反的控制。在这篇综述中,我们讨论了这个框架的一个假设延伸,其中直接通路纹状体神经元也介导强化和奖励,而间接通路神经元则介导惩罚和厌恶。