Lin M T, Lin S Z
Department of Physiology, National Cheng Kung University, Medical College, Tainan, Taiwan, Republic of China.
Chin J Physiol. 1990;33(3):247-53.
The effects of preganglionic decentralization of (sympathetic trunk resection) or post-ganglionic excision (ganglionectomy) of the superior cervical ganglia on cerebral blood flow and the formation of heat stroke were assessed in rabbits. An intravenous isotope method for external measurement of cerebral circulation time was applied to rabbits for determining cerebral blood flow. Heat stroke was induced by exposing animals to a high ambient temperature of 40 degrees C. The occurrence of loss of sensation, decreased muscle tone and unconsciousness was taken as the onset of heat stroke. The results showed that decentralization of the superior cervical ganglia enhanced the cerebral blood flow, whereas ganglionectomy reduced the cerebral blood flow. In addition, the latency for the onset of heat stroke and the survival time after the heat stroke were greatly prolonged by the former surgical procedure, but shortened by the later one. The data suggest that decentralization of the superior cervical ganglia attenuates formation or development of heat stroke by promoting an increase in cerebral blood flow in rabbits.
在兔子身上评估了颈上交感神经节前去传入（交感干切除术）或节后切除（神经节切除术）对脑血流量和中暑形成的影响。将一种用于外部测量脑循环时间的静脉注射同位素方法应用于兔子以测定脑血流量。通过将动物暴露于40摄氏度的高环境温度中来诱发中暑。将感觉丧失、肌张力降低和意识丧失的出现作为中暑的发作。结果表明，颈上交感神经节去传入增强了脑血流量，而神经节切除术则降低了脑血流量。此外，前一种手术方法大大延长了中暑发作的潜伏期和中暑后的存活时间，而后一种手术方法则缩短了这些时间。数据表明，颈上交感神经节去传入通过促进兔子脑血流量增加来减轻中暑的形成或发展。
