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沙特女性门诊患者全年存在维生素 D 缺乏。

Year-round vitamin D deficiency among Saudi female out-patients.

机构信息

College of Applied Medical Sciences, King Saud Bin Abdulaziz University for Health Sciences, P.O. Box 2490, Riyadh, Mail code 3129/Postal Code 11426, Saudi Arabia.

出版信息

Public Health Nutr. 2013 Mar;16(3):544-8. doi: 10.1017/S1368980012002947. Epub 2012 Jun 13.

Abstract

OBJECTIVE

The aim of the present study was to investigate vitamin D status among female out-patients in Saudi Arabia during the summer and winter seasons.

DESIGN

Data were retrospectively collected using medical record abstraction.

SETTING

A multidisciplinary hospital in Riyadh between January and December 2009.

SUBJECTS

Saudi females (age ≥19 years; n 1556) attending out-patient clinics for various complaints comprised the studied population. The population was subdivided into two groups depending on the date of their visit where blood samples were collected: summer (n 659) and winter groups (n 897). The summer group was further subdivided into premenopausal (age 19-49 years; n 425) and postmenopausal subgroups (age ≥50 years; n 234). Similarly, the winter group was subdivided into premenopausal (n 543) and postmenopausal subgroups (n 354). Serum levels of 25-hydroxyvitamin D (25(OH)D) were measured using HPLC.

RESULTS

The prevalence of vitamin D deficiency (25(OH)D <50 nmol/l) was high in both premenopausal and postmenopausal groups (80 % and 68 %, respectively) during the summer, as well as during the winter (85 % and 76 %, respectively).

CONCLUSIONS

A high prevalence of vitamin D deficiency among Saudi female out-patients was observed throughout the year despite the routine supplementation with 10-20 μg vitamin D3 for postmenopausal women. Clinicians should seriously consider determining the vitamin D status of Saudi females routinely and prescribing them proper supplementation.

摘要

目的

本研究旨在调查沙特阿拉伯女性门诊患者在夏季和冬季的维生素 D 状况。

设计

使用病历摘录回顾性收集数据。

地点

2009 年 1 月至 12 月期间,利雅得的一家多学科医院。

对象

沙特女性(年龄≥19 岁;n=1556),因各种疾病就诊于门诊。根据采血日期,将人群分为两组:夏季组(n=659)和冬季组(n=897)。夏季组进一步分为绝经前组(年龄 19-49 岁;n=425)和绝经后组(年龄≥50 岁;n=234)。同样,冬季组也分为绝经前组(n=543)和绝经后组(n=354)。采用 HPLC 法测定血清 25-羟维生素 D(25(OH)D)水平。

结果

夏季和冬季,绝经前和绝经后组的维生素 D 缺乏症(25(OH)D <50 nmol/l)患病率均较高(分别为 80%和 68%,85%和 76%)。

结论

尽管常规补充 10-20μg 维生素 D3 用于绝经后妇女,但沙特女性门诊患者中仍存在较高的维生素 D 缺乏症患病率。临床医生应认真考虑常规确定沙特女性的维生素 D 状态,并为其开具适当的补充剂。

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Year-round vitamin D deficiency among Saudi female out-patients.沙特女性门诊患者全年存在维生素 D 缺乏。
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