Center for Outcomes and Evidence, Agency for Healthcare Research and Quality, Rockville, MD 20850, USA.
Med Care. 2012 Jul;50 Suppl:S3-6. doi: 10.1097/MLR.0b013e3182588ed1.
A better alignment in the goals of the biomedical research enterprise and the health care delivery system can help fill the large gaps in our knowledge of the impact of clinical interventions on patient outcomes in the real world. There are several initiatives underway to align the research priorities of patients, providers, researchers, and policy makers. These include Agency for Healthcare Research and Quality (AHRQ)-supported projects to build flexible prospective clinical electronic data infrastructure that meet the needs of these diverse users. AHRQ has previously supported the creation of 2 distributed research networks as a new approach to conduct comparative effectiveness research (CER) while protecting a patient's confidential information and the proprietary needs of a clinical organization. It has applied its experience in building these networks in directing the American Recovery and Reinvestment Act funds for CER to support new clinical electronic infrastructure projects that can be used for several purposes including CER, quality improvement, clinical decision support, and disease surveillance. In addition, AHRQ has funded a new Electronic Data Methods forum to advance the methods in clinical informatics, research analytics, and governance by actively engaging investigators from the American Recovery and Reinvestment Act-funded projects and external stakeholders.
生物医学研究企业和医疗保健提供系统的目标更加一致，可以帮助填补我们在了解临床干预对现实世界中患者结果的影响方面的巨大知识空白。目前有几个正在进行的倡议，旨在协调患者、提供者、研究人员和政策制定者的研究重点。其中包括美国医疗保健研究与质量局（AHRQ）支持的项目，旨在建立灵活的前瞻性临床电子数据基础设施，以满足这些不同用户的需求。AHRQ 此前曾支持创建 2 个分布式研究网络，作为开展比较效果研究（CER）的一种新方法，同时保护患者的机密信息和临床组织的专有需求。它在建立这些网络方面的经验，指导了美国复苏与再投资法案（American Recovery and Reinvestment Act）资金用于 CER，以支持新的临床电子基础设施项目，这些项目可用于多种用途，包括 CER、质量改进、临床决策支持和疾病监测。此外，AHRQ 还资助了一个新的电子数据方法论坛，通过积极吸引美国复苏与再投资法案资助项目和外部利益相关者的研究人员，来推进临床信息学、研究分析和治理方面的方法。
