Health Economics and Outcomes Research, IMS Health, London, UK.
J Refract Surg. 2012 Jun;28(6):426-35. doi: 10.3928/1081597X-20120518-06.
To evaluate uncorrected distance visual acuity (UDVA) as well as uncorrected near visual acuity (UNVA) as outcomes in treating presbyopic cataract patients to assist clinicians and ophthalmologists in their decision-making process regarding available interventions.
Medline, Embase, and Evidence Based Medicine Reviews were systematically reviewed to identify studies reporting changes in UDVA and UNVA after cataract surgery in presbyopic patients. Strict inclusion/exclusion criteria were used to exclude any studies not reporting uncorrected visual acuity in a presbyopic population with cataracts implanted with multifocal intraocular lenses (IOLs). Relevant outcomes (UDVA and UNVA) were identified from the studies retrieved through the systematic review process.
Twenty-nine studies were identified that reported uncorrected visual acuities, including one study that reported uncorrected intermediate visual acuity. Nine brands of multifocal IOLs were identified in the search. All studies identified in the literature search reported improvements in UDVA and UNVA following multifocal IOL implantation. The largest improvements in visual acuity were reported using the Rayner M-Flex lens (Rayner Intraocular Lenses Ltd) (UDVA, binocular: 1.05 logMAR, monocular: 0.92 logMAR; UNVA, binocular and monocular: 0.83 logMAR) and the smallest improvements were reported using the Acri.LISA lens (Carl Zeiss Meditec) (UDVA, 0.21 decimal; UNVA, 0.51 decimal).
The results of this systematic review show the aggregate of studies reporting a beneficial increase in UDVA and UNVA with the use of multifocal IOLs in cataract patients with presbyopia, hence providing evidence to support the hypothesis that multifocal IOLs increase UDVA and UNVA in cataract patients.
评估未矫正远距视力(UDVA)和未矫正近距视力(UNVA)作为治疗老视白内障患者的结果,以帮助临床医生和眼科医生在针对可用干预措施做出决策时参考。
系统检索 Medline、Embase 和循证医学评论,以确定报告老视白内障患者白内障手术后 UDVA 和 UNVA 变化的研究。严格使用纳入/排除标准排除任何未报告植入多焦点人工晶状体(IOL)的白内障老视人群未矫正视力的研究。通过系统评价过程检索到的研究中确定了相关的结局(UDVA 和 UNVA)。
确定了 29 项报告未矫正视力的研究,其中包括一项报告未矫正中间视力的研究。在搜索中确定了 9 个品牌的多焦点 IOL。文献检索中确定的所有研究均报告了多焦点 IOL 植入后 UDVA 和 UNVA 的改善。使用 Rayner M-Flex 镜片(Rayner 眼内镜片有限公司)报告的视力改善最大(UDVA,双眼:1.05 logMAR,单眼:0.92 logMAR;UNVA,双眼和单眼:0.83 logMAR),而使用 Acri.LISA 镜片(卡尔蔡司医疗技术公司)报告的视力改善最小(UDVA,0.21 十进制;UNVA,0.51 十进制)。
本系统评价的结果表明,多项研究报告了在老视白内障患者中使用多焦点 IOL 可带来 UDVA 和 UNVA 的有益提高,从而为多焦点 IOL 可提高白内障患者的 UDVA 和 UNVA 的假设提供了证据支持。