Schädlich H J, Mohrmann G, Nekic M, Felgenhauer K
Neurological Clinic, University of Cologne, FRG.
Eur Neurol. 1990;30(5):302-4. doi: 10.1159/000117385.
Intrathecally synthesized antibodies against measles and rubella were determined in 221 patients with multiple sclerosis (MS) and in 476 control cases. A local production was detectable in more than 80% of the MS cases but in none of the control group. These results show that the demonstration of intrathecally synthesized antibodies against neurotropic viruses not related with respective infections may serve as helpful test in the diagnosis of MS.
在221例多发性硬化症（MS）患者和476例对照病例中测定了鞘内合成的抗麻疹和风疹抗体。在超过80%的MS病例中可检测到局部产生，但对照组中均未检测到。这些结果表明，检测鞘内合成的针对与相应感染无关的嗜神经病毒的抗体，可能有助于MS的诊断。
