Department of Psychiatry and Human Behavior, Brown University, 700 Butler Drive, Providence, RI 02906, USA.
J Psychiatr Res. 2012 Sep;46(9):1174-83. doi: 10.1016/j.jpsychires.2012.05.007. Epub 2012 Jun 12.
This study, the largest randomized controlled trial of treatment for major depressive disorder (MDD) in an incarcerated population to date, wave-randomized 38 incarcerated women (6 waves) with MDD who were attending prison substance use treatment to adjunctive group interpersonal psychotherapy (IPT) for MDD or to an attention-matched control condition. Intent-to-treat analyses found that IPT participants had significantly lower depressive symptoms at the end of 8 weeks of in-prison treatment than did control participants. Control participants improved later, after prison release. IPT's rapid effect on MDD within prison may reduce serious in-prison consequences of MDD.
这项研究是迄今为止针对监禁人群中重度抑郁症（MDD）治疗的最大规模随机对照试验，对 38 名患有 MDD 的被监禁女性（6 个波次）进行了波浪随机分组，这些女性正在参加监狱药物使用治疗，以附加团体人际心理治疗（IPT）治疗 MDD，或参加注意力匹配的对照组。意向治疗分析发现，IPT 参与者在入狱治疗的 8 周结束时的抑郁症状明显低于对照组参与者。对照组参与者在出狱后改善。IPT 在监狱内对 MDD 的快速作用可能会降低 MDD 的严重监禁后果。
