Department of Environmental Chemistry, IDAEA, CSIC, Jordi Girona, Barcelona, Spain.
Anal Bioanal Chem. 2012 Nov;404(9):2625-37. doi: 10.1007/s00216-012-6161-x. Epub 2012 Jun 14.
Dechlorane Plus, dechlorane 602, dechlorane 603 and dechlorane 604 are flame retardants that have been used for a long time as a substitute for mirex, but they have not been noticed as environmental contaminants until recently (2006). Regardless of their large molecular size and very high lipophilicity (log K(OW) > 9), Dechlorane Plus and related compounds have been detected in different aquatic and terrestrial species, supporting their bioaccumulation and biomagnification. Moreover, some studies showed different behaviour of the syn-Dechlorane Plus and anti-Dechlorane Plus isomers in the environment and different biomagnification factors in biota. This review describes the different analytical approaches applied to the determination of Dechlorane Plus and related compounds. Moreover, a summary of their levels in aquatic and terrestrial biota, as well as in humans, is presented, showing also current research results on their bioaccumulation and biomagnification potential. Finally, isomer-specific bioaccumulation of Dechlorane Plus is also discussed.
六氯丁二烯、六氯丁二烯 602、六氯丁二烯 603 和六氯丁二烯 604 是阻燃剂，它们长期以来一直被用作灭蚁灵的替代品，但直到最近（2006 年）才被发现是环境污染物。尽管其分子尺寸较大，疏水性（log K(OW) > 9）非常高，但已在不同的水生和陆地物种中检测到六氯丁二烯加合物和相关化合物，表明其具有生物蓄积性和生物放大性。此外，一些研究表明，顺式-六氯丁二烯加合物和反式-六氯丁二烯加合物异构体在环境中的行为不同，在生物群中的生物放大因子也不同。本文综述了用于测定六氯丁二烯加合物和相关化合物的不同分析方法。此外，还介绍了它们在水生和陆地生物群以及人类中的水平，同时还展示了目前关于其生物蓄积性和生物放大潜力的研究结果。最后，还讨论了六氯丁二烯加合物的对映体特异性生物蓄积性。
