College of Navigation, Dalian Maritime University, Dalian, 116026, China.
International Joint Research Centre for Persistent Toxic Substances (IJRC-PTS), College of Environmental Science and Engineering, Dalian Maritime University, Dalian, 116026, China.
Environ Sci Pollut Res Int. 2020 Feb;27(6):6269-6277. doi: 10.1007/s11356-019-07239-8. Epub 2019 Dec 21.
Dechlorane plus (DP) is a chlorinated flame retardant with high production volume (HPV) and is widely used in our daily necessities. In the present study, a laboratory-scale microcosm was built up to simulate the uptake, depuration, bioaccumulation, and stereoselective enrichment of DP in a lower concentration and equilibration condition. Common carp (Cyprinus carpio) were used for 32 days exposure and 32 days depuration. The concentration ratios of syn-DP to total DP (f values) in fish examined were lower than that in commercial products. Rate constants of uptake (k) and elimination (k) for the syn- and anti-DP were calculated using a first-order kinetic model. The uptake rate constants of syn- and anti-DP were 0.63 and 0.89 day, respectively. The depuration rate constants of syn-DP (0.11 day) were similar to anti-DP (0.096 day), suggesting that anti-DP is absorbed faster than syn-DP by common carp. The estimated bioconcentration factors for both syn-DP (5700 L/kg) and anti-DP (9300 L/kg) were higher than the bioconcentration hazard criteria outlined in the Stockholm Convention, suggesting the bioconcentration potential to aquatic organisms for DP.
得克隆（DP）是一种高生产量（HPV）的氯化阻燃剂，广泛应用于我们的日常用品中。在本研究中，构建了一个实验室规模的微宇宙，以模拟 DP 在低浓度和平衡条件下的摄取、净化、生物积累和立体选择性富集。鲤鱼（Cyprinus carpio）用于 32 天的暴露和 32 天的净化。研究中鱼类中 syn-DP 与总 DP（f 值）的浓度比低于商业产品。使用一阶动力学模型计算 syn-和 anti-DP 的摄取（k）和消除（k）速率常数。syn-和 anti-DP 的摄取速率常数分别为 0.63 和 0.89 天。syn-DP 的净化速率常数（0.11 天）与 anti-DP（0.096 天）相似，表明 anti-DP 比 syn-DP 被鲤鱼更快地吸收。syn-DP（5700 L/kg）和 anti-DP（9300 L/kg）的估算生物浓缩因子均高于斯德哥尔摩公约规定的生物浓缩危害标准，表明 DP 对水生生物具有生物浓缩潜力。
