Department of Ophthalmology, HELIOS Klinikum Erfurt, Nordhäuserstrasse 74, 99089 Erfurt, Germany.
Graefes Arch Clin Exp Ophthalmol. 2013 Jan;251(1):349-55. doi: 10.1007/s00417-012-2064-y. Epub 2012 Jun 14.
This prospective study focused on the results of a novel method for refractive correction, femtosecond lenticule extraction (ReLEx®) in hyperopia, and reports the first 47 eyes.
In 47 hyperopic eyes (26 patients), both a flap and a lenticule of intrastromal corneal tissue were simultaneously cut utilizing the Carl Zeiss Meditec AG (CZM) 200 kHz VisuMax femtosecond laser system. Thereafter, the lenticule was manually removed and the flap repositioned. Forty two out of 47 hyperopic eyes of the treatment group completed the final 9-month follow-up. The patients mean age was 42.3 (±9.0) years. Their mean preoperative spherical equivalent (SE) was +2.8 (±1.3) D. UCVA and BSCVA after 9 months, objective and manifest refraction, as well as slit-lamp examination and side-effects were evaluated.
Nine months postoperatively, 64 % of eyes treated were within ±1.0 D, and 38 % of eyes within ±0.5 D of intended correction. One of 47 eyes (2.1 %) lost more than 2 Snellen lines; none of the eyes had a UCVA less than 0.5. However, stability was less impressive when compared to ReLEx for the correction of myopia.
First data suggest that ReLEx is a feasible and effective procedure for treatment of hyperopia. Further research is needed to improve predictability and effectiveness of the procedure for the correction of hyperopia.
本前瞻性研究聚焦于一种新的远视屈光矫正方法（飞秒激光透镜切除术，ReLEx®）的结果，报道了首批 47 只眼的结果。
在 47 只远视眼中（26 例患者），利用卡尔蔡司医疗技术公司（CZM）200 kHz VisuMax 飞秒激光系统同时切割角膜层间的瓣和透镜。然后手动取出透镜并重新定位瓣。治疗组的 47 只远视眼中有 42 只完成了最终的 9 个月随访。患者平均年龄为 42.3（±9.0）岁。他们的平均术前球镜等效值（SE）为+2.8（±1.3）D。术后 9 个月评估了患者的最佳矫正视力（UCVA）和标准视力（BSCVA）、客观和主观屈光、裂隙灯检查和不良反应。
术后 9 个月，64%的治疗眼屈光度在±1.0 D 以内，38%的治疗眼屈光度在±0.5 D 以内。47 只眼中有 1 只（2.1%）视力下降超过 2 行；没有 1 只眼的 UCVA 低于 0.5。然而，与 ReLEx 治疗近视相比，其稳定性不太令人印象深刻。
初步数据表明，ReLEx 是治疗远视的一种可行且有效的方法。需要进一步研究以提高该方法治疗远视的可预测性和有效性。
