Sionidou M, Spyratos D, Chloros D, Sichletidis L
Pulmonary Department, Aristotle University of Thessaloniki, Thessaloniki, Greece.
BMJ Case Rep. 2011 May 10;2011:bcr0120113740. doi: 10.1136/bcr.01.2011.3740.
Treatment with interferon (IFN) can precipitate a variety of inflammatory conditions, including sarcoidosis. Although many other systems can be affected, the clinical picture in this case mostly includes cutaneous and pulmonary symptoms. The prognosis is better than the idiopathic form of the disease, and the most effective treatment is considered the discontinuation of antivirus therapy alone or in combination with corticosteroid administration. The authors present the case of a 36-year-old man who developed sarcoidosis stage I after 2 years of IFNα therapy for polycythemia vera.
用干扰素（IFN）治疗可引发多种炎症性疾病，包括结节病。尽管许多其他系统可能受到影响，但该病例的临床表现主要包括皮肤和肺部症状。其预后优于该疾病的特发性形式，最有效的治疗方法被认为是单独停用抗病毒治疗或与皮质类固醇联合使用。作者介绍了一名36岁男性的病例，该患者在接受干扰素α治疗真性红细胞增多症2年后发展为I期结节病。
