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本文引用的文献

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Impact of time to antibiotics on survival in patients with severe sepsis or septic shock in whom early goal-directed therapy was initiated in the emergency department.在急诊科开始早期目标导向治疗的严重脓毒症或感染性休克患者中,抗生素使用时间对生存的影响。
Crit Care Med. 2010 Apr;38(4):1045-53. doi: 10.1097/CCM.0b013e3181cc4824.
2
BTS guidelines for the management of community acquired pneumonia in adults: update 2009.英国胸科学会成人社区获得性肺炎管理指南:2009年更新版
Thorax. 2009 Oct;64 Suppl 3:iii1-55. doi: 10.1136/thx.2009.121434.
3
Surviving Sepsis Campaign: international guidelines for management of severe sepsis and septic shock: 2008.拯救脓毒症运动:严重脓毒症和脓毒性休克治疗国际指南:2008年版
Crit Care Med. 2008 Jan;36(1):296-327. doi: 10.1097/01.CCM.0000298158.12101.41.
4
The atypical pneumonias: clinical diagnosis and importance.非典型肺炎:临床诊断及重要性
Clin Microbiol Infect. 2006 May;12 Suppl 3:12-24. doi: 10.1111/j.1469-0691.2006.01393.x.
5
Clinical outcomes for hospitalized patients with Legionella pneumonia in the antigenuria era: the influence of levofloxacin therapy.抗原尿时代住院军团菌肺炎患者的临床结局:左氧氟沙星治疗的影响。
Clin Infect Dis. 2005 Mar 15;40(6):794-9. doi: 10.1086/428059. Epub 2005 Feb 17.
6
Can Legionnaires disease be diagnosed by clinical criteria? A critical review.军团病能否通过临床标准进行诊断?一项批判性综述。
Chest. 2001 Oct;120(4):1049-53. doi: 10.1378/chest.120.4.1049.
7
The radiologic manifestations of Legionnaire's disease. The Ohio Community-Based Pneumonia Incidence Study Group.军团病的放射学表现。俄亥俄州社区肺炎发病率研究小组。
Chest. 2000 Feb;117(2):398-403. doi: 10.1378/chest.117.2.398.
8
Prognostic factors of severe Legionella pneumonia requiring admission to ICU.需要入住重症监护病房的重症军团菌肺炎的预后因素。
Am J Respir Crit Care Med. 1997 Nov;156(5):1467-72. doi: 10.1164/ajrccm.156.5.97-04039.
9
Legionellosis.军团病
N Engl J Med. 1997 Sep 4;337(10):682-7. doi: 10.1056/NEJM199709043371006.
10
Community-acquired pneumonia: the annual cost to the National Health Service in the UK.社区获得性肺炎:英国国民医疗服务体系的年度成本
Eur Respir J. 1997 Jul;10(7):1530-4. doi: 10.1183/09031936.97.10071530.

重症监护环境中军团菌的管理。

Management of Legionella in the intensive care setting.

作者信息

Harris Nicholas John, Harris Anna Claire Victoria, Spiro Michael

机构信息

Whipps Cross University Hospital NHS Trust, London, UK.

出版信息

BMJ Case Rep. 2011 May 12;2011:bcr1220103587. doi: 10.1136/bcr.12.2010.3587.

DOI:10.1136/bcr.12.2010.3587
PMID:22696745
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3094801/
Abstract

In August 2009, during the swine flu pandemic, a 55-year-old male presented to the Emergency Department (ED) with shortness-of-breath and chest pain. He had experienced diarrhoea and vomiting during the 3 weeks preceding admission, and so had sought the advice of his General Practitioner (GP) who had prescribed a course of oseltamivir (Tamiflu). Despite this, his symptoms had worsened, and on arrival in the ED he was found to be tachypnoeic, tachycardic, feverish, anuric and in type I respiratory failure with a compensated metabolic acidosis. He subsequently became hypotensive, and so was transferred to the Intensive Care Unit (ICU) for supportive treatment of three organ failures. Investigation revealed that he was suffering from Legionnaires disease. This required a prolonged inpatient stay owing to both disease and treatment related complications.

摘要

2009年8月,在猪流感大流行期间,一名55岁男性因呼吸急促和胸痛被送往急诊科。入院前3周,他出现腹泻和呕吐症状,因此向全科医生咨询,医生给他开了一个疗程的奥司他韦(达菲)。尽管如此,他的症状仍在恶化,抵达急诊科时,发现他呼吸急促、心跳过速、发烧、无尿,处于I型呼吸衰竭并伴有代偿性代谢性酸中毒。随后他出现低血压,因此被转至重症监护病房,对其三个器官功能衰竭进行支持治疗。调查显示,他患有军团病。由于疾病和治疗相关并发症,他需要长时间住院治疗。