与乳糜泻相关的快速进展性终末期心力衰竭患者的心脏移植
Heart transplantation in rapidly progressive end-stage heart failure associated with celiac disease.
作者信息
Barrio Juan P, Cura Geraldine, Ramallo German, Diez Mirta, Vigliano Carlos A, Katus Hugo A, Mereles Derliz
机构信息
Servicio de Cardiología, Hospital Interzonal Dr José Penna, Bahia Blanca, Argentina.
出版信息
BMJ Case Rep. 2011 May 12;2011:bcr1220103624. doi: 10.1136/bcr.12.2010.3624.
Abstract
Celiac disease is characterised by chronic immune-mediated malabsorption in genetically susceptible individuals induced by gluten proteins present in wheat, barley and rye. It occurs in adults and children at rates approaching 1% of the population. Cardiomyopathy associated with celiac disease is infrequent. The authors present here a first case of a severe progressive dilated cardiomyopathy that required heart transplantation in young woman with celiac disease.
摘要
乳糜泻的特征是，在遗传易感性个体中，由小麦、大麦和黑麦中的麸质蛋白引发慢性免疫介导的吸收不良。乳糜泻在成人和儿童中的发病率接近总人口的1%。与乳糜泻相关的心肌病并不常见。本文作者报告了首例患有乳糜泻的年轻女性发生严重进行性扩张型心肌病并需要进行心脏移植的病例。
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