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前交叉韧带移植物的失败位置在同种异体移植物和自体移植物之间存在差异。

ACL graft failure location differs between allografts and autografts.

作者信息

Magnussen Robert A, Taylor Dean C, Toth Alison P, Garrett William E

机构信息

Department of Orthopaedic Surgery, Sports Health and Performance Institute, The Ohio State University Medical Center, Columbus, OH, 43221, USA.

出版信息

Sports Med Arthrosc Rehabil Ther Technol. 2012 Jun 14;4(1):22. doi: 10.1186/1758-2555-4-22.

Abstract

BACKGROUND

Between 5 and 20% of patients undergoing ACL reconstruction fail and require revision. Animal studies have demonstrated slower incorporation of allograft tissue, which may affect the mechanism of graft failure. The purpose of this study is to determine the location of traumatic graft failure following ACL reconstruction and investigate differences in failure patterns between autografts and allografts.

METHODS

The medical records of 34 consecutive patients at our center undergoing revision ACL reconstruction following a documented traumatic re-injury were reviewed. Graft utilized in the primary reconstruction, time from initial reconstruction to re-injury, activity at re-injury, time to revision reconstruction, and location of ACL graft tear were recorded.

RESULTS

Median patient age at primary ACL reconstruction was 18.5 years (range, 13-39 years). The primary reconstructions included 20 autografts (13 hamstrings, 6 patellar tendons, 1 iliotibial band), 12 allografts (5 patellar tendon, 5 tibialis anterior tendons, 2 achilles tendons), and 2 unknown. The median time from primary reconstruction to re-injury was 1.2 years (range, 0.4 - 17.6 years). The median time from re-injury to revision reconstruction was 10.4 weeks (range, 1 to 241 weeks). Failure location could be determined in 30 patients. In the autograft group 14 of 19 grafts failed near their femoral attachment, while in the allograft group 2 of 11 grafts failed near their femoral attachment (p < 0.02).

CONCLUSIONS

When ACL autografts fail traumatically, they frequently fail near their femoral origin, while allograft reconstructions that fail are more likely to fail in other locations or stretch.

LEVEL OF EVIDENCE

Level III - Retrospective cohort study.

摘要

背景

在接受前交叉韧带(ACL)重建的患者中,有5%至20%的患者手术失败,需要进行翻修手术。动物研究表明,同种异体移植组织的整合较慢,这可能会影响移植失败的机制。本研究的目的是确定ACL重建术后创伤性移植失败的位置,并调查自体移植和同种异体移植之间失败模式的差异。

方法

回顾了我们中心34例因记录在案的创伤性再次损伤而接受ACL翻修重建的连续患者的病历。记录初次重建时使用的移植物、从初次重建到再次损伤的时间、再次损伤时的活动情况、到翻修重建的时间以及ACL移植物撕裂的位置。

结果

初次ACL重建时患者的中位年龄为18.5岁(范围为13至39岁)。初次重建包括20例自体移植(13例腘绳肌、6例髌腱、1例髂胫束)、12例同种异体移植(5例髌腱、5例胫前肌腱、2例跟腱)以及2例情况不明。从初次重建到再次损伤的中位时间为1.2年(范围为0.4至17.6年)。从再次损伤到翻修重建的中位时间为10.4周(范围为1至241周)。30例患者的失败位置可以确定。在自体移植组中,19例移植物中有14例在其股骨附着处附近失败,而在同种异体移植组中,11例移植物中有2例在其股骨附着处附近失败(p<0.02)。

结论

当ACL自体移植因创伤而失败时,它们通常在其股骨起点附近失败,而失败的同种异体移植重建更有可能在其他位置失败或发生拉伸。

证据级别

III级——回顾性队列研究。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6579/3411415/8a4e0aac98cb/1758-2555-4-22-1.jpg

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