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毫米波反射法分析人体皮肤组织。

Analysis of human skin tissue by millimeter-wave reflectometry.

机构信息

Eindhoven University of Technology, Eindhoven, The Netherlands.

出版信息

Skin Res Technol. 2013 Feb;19(1):e209-16. doi: 10.1111/j.1600-0846.2012.00629.x. Epub 2012 Jun 14.

Abstract

BACKGROUND/PURPOSE: Millimeter-wave reflectometry is a potentially interesting technique to analyze the human skin in vivo in order to determine the water content locally in the skin. Purpose of this work is to investigate the possibility of skin-tissue differentiation. In addition, it addresses the influence of the pressure of the probe on the skin, the influence of an air gap between probe and skin as well as the influence of a bandage between probe and skin.

METHODOLOGY

Reflection coefficients at various positions on the skin are measured in the 40-60 GHz range and the examined effects are quantified in terms of magnitude and phase of the reflection coefficient. Also, the possibility to perform tissue differentiation is quantified.

RESULTS

It is indicated that differentiation of skin tissue can be performed on the basis of the magnitude of the reflection coefficient provided that no air gap exists between probe and skin. The influence of probe pressure can be substantial, in particular for phase measurements. The presence of an air gap between probe and skin reduces the differentiation capability of the considered measurement technique, whereas a bandage between probe and skin did not significantly affect the differentiation power.

CONCLUSION

The results of this work confirm the potential of millimeter-wave reflectometry for determination of the water content in skin tissue which may lead to interesting applications as early detection of skin cancer and through-bandage monitoring of wounds.

摘要

背景/目的:毫米波反射计是一种有潜力的分析人体皮肤的技术,可用于确定皮肤内的局部水分含量。本研究旨在探讨皮肤组织区分的可能性。此外,还研究了探头对皮肤的压力、探头与皮肤之间的气隙以及探头与皮肤之间的绷带对测量的影响。

方法

在 40-60GHz 范围内测量皮肤不同位置的反射系数,并根据反射系数的幅度和相位来量化所研究的影响。此外,还量化了进行组织区分的可能性。

结果

结果表明,只要探头与皮肤之间不存在气隙,就可以根据反射系数的幅度对皮肤组织进行区分。探头压力的影响可能很大,特别是对于相位测量。探头与皮肤之间存在气隙会降低所考虑测量技术的区分能力,而探头与皮肤之间的绷带则不会显著影响区分能力。

结论

这项工作的结果证实了毫米波反射计在确定皮肤组织水分含量方面的潜力,这可能会为早期发现皮肤癌和通过绷带监测伤口等提供有趣的应用。

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