Department of Ophthalmology, Hamilton Glaucoma Center, University of California, La Jolla, San Diego, CA, USA.
Expert Rev Med Devices. 2012 May;9(3):225-31. doi: 10.1586/erd.12.14.
Intraocular pressure (IOP) is a major risk factor for glaucoma and lowering IOP remains the mainstay of glaucoma treatment. Current glaucoma management usually relies on single IOP measurements during clinic hours despite the fact that the majority of glaucoma patients have their highest IOP levels outside clinic hours. The fact that these IOP peaks go largely undetected may explain why certain patients have progressive disease despite treatment. The search for devices to facilitate continuous 24-h IOP monitoring started over 50 years ago, but only recently have technological advances provided clinicians with a device for continuous IOP monitoring. We discuss the shortcomings of Goldmann Applanation Tonometry, the current gold standard for tonometry, and our experience with the SENSIMED Triggerfish®, a telemetric contact lens sensor for 24-h IOP monitoring. It may be possible to integrate 24-h continuous IOP monitoring into clinical practice, and this has the potential to contribute to the reduction of glaucoma-related vision loss.
眼压 (IOP) 是青光眼的主要危险因素，降低 IOP 仍然是青光眼治疗的主要方法。尽管大多数青光眼患者的眼压水平在就诊时间之外最高，但目前的青光眼管理通常依赖于就诊时间内的单次 IOP 测量。这些眼压峰值大部分未被检测到，这可能解释了为什么某些患者尽管接受了治疗，疾病仍在进展。寻找有助于连续 24 小时眼压监测的设备已经有 50 多年的历史了，但直到最近，技术进步才为临床医生提供了连续眼压监测设备。我们讨论了 Goldmann 压平眼压计的缺点，Goldmann 压平眼压计是眼压测量的金标准，以及我们对 SENSIMED Triggerfish®的经验，这是一种用于 24 小时眼压监测的遥测接触镜传感器。将 24 小时连续眼压监测纳入临床实践是可能的，这有可能有助于减少与青光眼相关的视力丧失。
