Gaton Dan D, Ehrenberg Miriam, Lusky Moshe, Wussuki-Lior Orly, Dotan Gad, Weinberger Dov, Snir Moshe
Department of Ophthalmology, Rabin Medical Center, Beilinson Campus, Petach Tikva, Israel.
Curr Eye Res. 2010 Jun;35(6):475-9. doi: 10.3109/02713681003678824.
To evaluate the stability of successive applanation tonometry measurements in glaucomatous eyes.
A prospective, comparative, randomized, and evaluator-masked study was conducted in a tertiary medical center. Sixty-seven patients with glaucoma attending our glaucoma clinic underwent four successive intraocular pressure (IOP) measurements with Goldmann-type applanation tonometry. Findings were compared with 70 patients scheduled for cataract surgery, similar in age and sex. The results were statistically analyzed with repeated measures analysis.
In the glaucoma group, the difference between the first and second IOP measurements was statistically significant (15.94 mmHg vs 14.9 mmHg, p < 0.0001), as was the decrease in IOP from the first measurement to each of the other successive measurements. No significant change in IOP was noted in the control group (mean, 13.7 mmHg).
Patients with glaucoma show a decrease in IOP on repeated applanation tonometry measurements. By contrast, in individuals without glaucoma, no significant decrease in IOP on repeated applanation tonometry measurements was found.
评估青光眼患者多次压平眼压测量的稳定性。
在一家三级医疗中心进行了一项前瞻性、对比性、随机且评估者盲法的研究。67名就诊于我们青光眼门诊的青光眼患者使用戈德曼式压平眼压计进行了连续4次眼压(IOP)测量。将结果与70名计划进行白内障手术、年龄和性别相近的患者进行比较。采用重复测量分析对结果进行统计学分析。
在青光眼组中,首次和第二次IOP测量之间的差异具有统计学意义(15.94 mmHg对14.9 mmHg,p < 0.0001),从首次测量到其他连续测量的IOP下降情况也是如此。对照组中未观察到IOP有显著变化(平均值为13.7 mmHg)。
青光眼患者在重复压平眼压测量时IOP会降低。相比之下,在无青光眼的个体中,重复压平眼压测量未发现IOP有显著降低。