动员内源性干细胞进行修复和再生：我们做到了吗？

Mobilizing endogenous stem cells for repair and regeneration: are we there yet?

机构信息

Developmental and Stem Cell Biology Program, Hospital for Sick Children, Toronto M5G 1L7, Canada; McEwen Center for Regenerative Medicine, University of Toronto, Toronto M5G 1X5, Canada; Department of Molecular Genetics, University of Toronto, Toronto M5G 1X5, Canada; Department of Physiology, University of Toronto, Toronto M5G 1X5, Canada.

Cell Biology Program, Hospital for Sick Children, Toronto M5G 1L7, Canada; Department of Molecular Genetics, University of Toronto, Toronto M5G 1X5, Canada.

出版信息

Cell Stem Cell. 2012 Jun 14;10(6):650-652. doi: 10.1016/j.stem.2012.05.004.

DOI:10.1016/j.stem.2012.05.004

PMID:22704501

Abstract

Harnessing endogenous repair mechanisms to promote tissue regeneration in situations in which it does not normally occur has long been a goal in biomedical science. Recent advances in tissue stem cells indicate that this goal may now be achievable. Here we consider both the promise and the hurdles we still have to overcome.

摘要

利用内源性修复机制促进在正常情况下不会发生的组织再生一直是生物医学科学的一个目标。最近在组织干细胞方面的进展表明，这一目标现在可能是可以实现的。在这里，我们既考虑了这一目标的前景，也考虑了我们仍然需要克服的障碍。