INSERM UMR1094, Tropical Neuroepidemiology, Limoges, France.
Eur J Vasc Endovasc Surg. 2012 Aug;44(2):164-9. doi: 10.1016/j.ejvs.2012.05.019. Epub 2012 Jun 15.
Peripheral artery disease (PAD) is a common condition in Western countries, mostly in the elderly. Little is known about the epidemiology of PAD in Africa. We sought to determine the prevalence of this condition in the elderly in two community-dwelling cohorts in Central Africa.
Prospective cross-sectional survey in general population over the age of 65 years in Bangui (Central African Republic) and Brazzaville (Congo).
We conducted a systematic door-to-door survey in two representative districts of each city. Demographic, clinical and biological data were collected. The ankle-brachial index (ABI) was used to detect PAD (ABI ≤ 0.90).
Among the 976 participants, the prevalence of PAD was 15.0% in Bangui and 32.4% in Brazzaville, increasing with age. Adjusted to age, regular alcohol consumption was protective for women in Bangui (OR = 0.50, CI95%:0.25-0.98) and men in Brazzaville (OR = 0.43, CI95%:0.21-0.88). Hypertension was associated with PAD in women (OR = 4.14, CI95%:1.65-10.42 in Bangui and OR = 2.17, CI95%:1.16-4.06 in Brazzaville). Diabetes and smoking showed different associations according to gender and city.
This first population study in Central Africa highlights the high prevalence of PAD in the older population, and emphasizes specificities regarding the risk factors, being different from data published in Western countries.
外周动脉疾病（PAD）是西方国家的一种常见疾病，主要发生在老年人中。关于非洲 PAD 的流行病学情况知之甚少。我们旨在确定中非两个社区居住队列中老年人的这种疾病的患病率。
在年龄在 65 岁以上的班吉（中非共和国）和布拉柴维尔（刚果）的普通人群中进行前瞻性横断面调查。
我们在每个城市的两个代表性地区进行了系统的逐户调查。收集了人口统计学、临床和生物学数据。使用踝臂指数（ABI）来检测 PAD（ABI≤0.90）。
在 976 名参与者中，PAD 在班吉的患病率为 15.0%，在布拉柴维尔为 32.4%，且随年龄增长而增加。调整年龄后，在班吉，女性中规律饮酒具有保护作用（OR=0.50，95%CI：0.25-0.98），而在布拉柴维尔，男性中规律饮酒具有保护作用（OR=0.43，95%CI：0.21-0.88）。在女性中，高血压与 PAD 相关（OR=4.14，95%CI：1.65-10.42 在班吉和 OR=2.17，95%CI：1.16-4.06 在布拉柴维尔）。糖尿病和吸烟与性别和城市有关，具有不同的相关性。
这是中非进行的第一项人群研究，强调了在老年人群中 PAD 的高患病率，并强调了与在西方国家发表的数据不同的风险因素的特殊性。
