International Longevity Centre UK, London, UK.
J Epidemiol Community Health. 2013 Jan;67(1):48-55. doi: 10.1136/jech-2011-200867. Epub 2012 Jun 15.
In order to consider the potential contribution of universal versus targeted prevention interventions, the authors examined what is the distribution of established risk variables for teenage motherhood? from where in these distributions do births arise? and how does this distribution/determination of risk vary between studies?
Secondary data analysis of three British longitudinal studies.
For all cohorts and variables, the 'risk' category was the least frequent. Continuous risk factors were normally distributed. A high rate of teenage motherhood within a risk category often translated into low 'contribution' to the overall rate (eg, expectation to leave school at the minimum age among the 1989/1990-born cohort) and vice versa. Most young women had a low probability of teenage motherhood. For any targeting strategy, combining risk factors and a low threshold of predicted probability would be necessary to achieve adequate sensitivity. Assessing between-cohort applicability of findings, the authors find that the numbers of teenage parents is poorly estimated and estimates of the variability and direction of risk may also be inadequate.
With reference to a number of established risk factors, there is not a core of easily identifiable multiply disadvantaged girls who go on to constitute the majority of teenage mothers in these studies. While individual risk factors are unlikely to enable targeting, a composite may have some limited potential, albeit with a low threshold for 'risk' and with the caveat that evidence from one population may not inform good targeting in another. It is likely that universal approaches will have more impact.
为了考虑普遍预防干预与有针对性预防干预的潜在贡献,作者研究了以下问题:有哪些已确立的少女生育风险变量?这些分布中从哪里开始出现生育现象?以及这种风险分布/确定在不同研究中有何差异?
对三项英国纵向研究进行二次数据分析。
对于所有队列和变量,“风险”类别都是最不常见的。连续风险因素呈正态分布。在风险类别中,较高的少女生育率往往意味着对总体率的贡献较低(例如,1989/1990 年出生队列中最低年龄离校的期望),反之亦然。大多数年轻女性生育少女的可能性较低。对于任何靶向策略,都需要将风险因素结合起来,并设定较低的预测概率阈值,以实现足够的敏感性。评估研究结果在队列间的适用性,作者发现少女父母的数量估计不足,风险的可变性和方向的估计也可能不足。
对于许多已确立的风险因素,这些研究中大多数少女母亲并非核心人群,她们是那些容易识别的、多重劣势的女孩。虽然个别风险因素不太可能实现靶向,但综合因素可能具有一定的潜在可能性,尽管“风险”的门槛较低,并且需要注意的是,来自一个人群的证据可能无法为另一个人群提供良好的靶向依据。普遍方法可能更具影响力。