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Administration of tramadol or ibuprofen increases the INR level in patients on warfarin.

作者信息

Juel Jacob, Pedersen Torben Brøchner, Langfrits Christian Sigvald, Jensen Svend Eggert

出版信息

Eur J Clin Pharmacol. 2013 Feb;69(2):291-2. doi: 10.1007/s00228-012-1325-3. Epub 2012 Jun 17.

DOI:10.1007/s00228-012-1325-3
PMID:22706619
Abstract
摘要

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本文引用的文献

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Gastrointestinal safety of nonsteroidal antiinflammatory drugs and selective cyclooxygenase-2 inhibitors in patients on warfarin.华法林治疗患者的非甾体抗炎药和选择性环氧化酶-2 抑制剂的胃肠道安全性。
Ann Pharmacother. 2009 Nov;43(11):1765-73. doi: 10.1345/aph.1M284. Epub 2009 Oct 6.
2
Increased liability of tramadol-warfarin interaction in individuals with mutations in the cytochrome P450 2D6 gene.细胞色素P450 2D6基因突变个体中曲马多与华法林相互作用的风险增加。
Eur J Clin Pharmacol. 2004 Jul;60(5):369-72. doi: 10.1007/s00228-004-0783-7. Epub 2004 Jun 10.
3
Prospective evaluation of the quality of oral anticoagulation management in an outpatient clinic and in general practices.
曲马多与华法林联用导致出血和国际标准化比值升高
P T. 2019 Sep;44(9):546-548.
4
PharmGKB summary: ibuprofen pathways.PharmGKB总结：布洛芬作用途径。
Pharmacogenet Genomics. 2015 Feb;25(2):96-106. doi: 10.1097/FPC.0000000000000113.
5
Adherence to guidelines for avoiding drug interactions associated with warfarin--a Nationwide Swedish Register Study.遵循避免与华法林相关药物相互作用的指南——一项瑞典全国性登记研究
PLoS One. 2014 May 15;9(5):e97388. doi: 10.1371/journal.pone.0097388. eCollection 2014.
Thromb Res. 2002 Jan 15;105(2):103-8. doi: 10.1016/s0049-3848(01)00401-7.
4
Nonsteroidal antiinflammatory drug use in patients receiving warfarin: emphasis on nabumetone.
Am J Med. 1993 Aug 9;95(2A):30S-34S. doi: 10.1016/0002-9343(93)90394-5.
5
Interaction of ibuprofen and warfarin on primary haemostasis.
Br J Rheumatol. 1989 Feb;28(1):46-9. doi: 10.1093/rheumatology/28.1.46.