Bondarenko T I, Maĭboroda E A, Mikhaleva I I, Prudchenko I A
Adv Gerontol. 2012;25(1):132-8.
The authors show that exogenous delta-sleep inducing peptide (DSIP) injected subcutaneously to the rats in the age of 2-24 months of postnatal development in a dose of 100 mg/kg of animal body weight in courses for 5 consecutive days every month, has a hepatoprotective effect. DSIP does not affect the functional activity of the pancreas, and is not involved in the regulation of calcium homeostasis in the physiological aging of the organism.
作者表明,在出生后2至24个月龄的大鼠皮下注射外源性δ-睡眠诱导肽(DSIP),剂量为每千克动物体重100毫克,每月连续5天给药,具有肝脏保护作用。DSIP不影响胰腺的功能活性,也不参与机体生理衰老过程中钙稳态的调节。