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[δ-睡眠诱导肽对大鼠生理衰老过程中某些器官和组织功能活性的影响]

[Effect of delta-sleep inducing peptide on the functional activity of some organs and tissues of rats during physiological aging].

作者信息

Bondarenko T I, Maĭboroda E A, Mikhaleva I I, Prudchenko I A

出版信息

Adv Gerontol. 2012;25(1):132-8.

PMID:22708458
Abstract

The authors show that exogenous delta-sleep inducing peptide (DSIP) injected subcutaneously to the rats in the age of 2-24 months of postnatal development in a dose of 100 mg/kg of animal body weight in courses for 5 consecutive days every month, has a hepatoprotective effect. DSIP does not affect the functional activity of the pancreas, and is not involved in the regulation of calcium homeostasis in the physiological aging of the organism.

摘要

作者表明,在出生后2至24个月龄的大鼠皮下注射外源性δ-睡眠诱导肽(DSIP),剂量为每千克动物体重100毫克,每月连续5天给药,具有肝脏保护作用。DSIP不影响胰腺的功能活性,也不参与机体生理衰老过程中钙稳态的调节。

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