定量分析 miroestrol 和 kwakhurin，以标准化泰国产“Kwao Keur”（野葛根），并建立简单的分离高雌激素 miroestrol 和去甲氧基 miroestrol 的程序。
Quantitative analysis of miroestrol and kwakhurin for standardisation of Thai miracle herb 'Kwao Keur' (Pueraria mirifica) and establishment of simple isolation procedure for highly estrogenic miroestrol and deoxymiroestrol.
机构信息
Graduate School of Pharmaceutical Sciences, Chiba University, 1-8-1 Inohana, Chuo, Chiba 260-8675, Japan.
出版信息
Nat Prod Res. 2013 Mar;27(4-5):371-8. doi: 10.1080/14786419.2012.695370. Epub 2012 Jun 18.
PMID:22708703
Abstract
Quantitative analysis of miroestrol (1) and kwakhurin (3) by HPLC, leading to standardisation of commercially available Thai miracle herb 'Kwao Keur' which has been identified with Pueraria mirifica, was established using independent solvent systems. The simple isolation procedure of highly estrogenic miroestrol (1) and deoxymiroestrol (2) from P. mirifica was also proposed.
摘要
采用 HPLC 对 miroestrol（1）和 kwakhurin（3）进行定量分析，建立了用独立溶剂系统对已鉴定为泰国神奇草药“Kwao Keur”（葛根）的商业产品进行标准化的方法。还提出了从葛根中简单分离高雌激素 miroestrol（1）和 deoxymiroestrol（2）的方法。
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