Kuan Aaron T, Golovchenko Jene A
Appl Phys Lett. 2012 May 21;100(21):213104-2131044. doi: 10.1063/1.4719679.
Recent work on protein nanopores indicates that single molecule characterization (including DNA sequencing) is possible when the length of the nanopore constriction is about a nanometer. Solid-state nanopores offer advantages in stability and tunability, but a scalable method for creating nanometer-thin solid-state pores has yet to be demonstrated. Here we demonstrate that solid-state nanopores with nanometer-thin constrictions can be produced by "cold ion beam sculpting," an original method that is broadly applicable to many materials, is easily scalable, and requires only modest instrumentation.
近期关于蛋白质纳米孔的研究表明，当纳米孔收缩部分的长度约为一纳米时，单分子表征（包括DNA测序）是可行的。固态纳米孔在稳定性和可调性方面具有优势，但尚未证明有一种可扩展的方法来制造纳米级薄的固态孔。在这里，我们证明了具有纳米级薄收缩部分的固态纳米孔可以通过“冷离子束雕刻”来制造，这是一种原始方法，广泛适用于多种材料，易于扩展，并且只需要普通的仪器设备。
