Department of Oral and Maxillofacial Pathology & Microbiology, College of Dental Sciences & Hospital, Karnataka, India.
Braz Oral Res. 2012 Jul-Aug;26(4):330-4. doi: 10.1590/s1806-83242012005000007. Epub 2012 Jun 19.
The purpose of this study was to determine the prevalence of odontogenic cysts and to identify their clinico-pathological features among patients by studying biopsy specimens obtained from the archives of the Department of Oral and Maxillofacial Pathology, College of Dental Sciences, Davangere, Karnataka, India, during the past 10 years. Data for the study were retrieved from the case records of patients fitting the histological classification of the World Health Organization (1992). Analyzed clinical variables included age, gender, anatomical location, and histological diagnosis. Of the 2275 biopsy reports analyzed, 194 cases (8.5%) were jaw cysts, including odontogenic (6.7%) and nonodontogenic cysts (0.25%). Odontogenic cysts included 69.3% radicular, 20.3% dentigerous, 5.2% keratinizing odontogenic, 3.3% residual, and 1.9% other cysts, such as lateral periodontal, botryoid odontogenic, and gingival cysts. The most frequent clinical manifestation was swelling, followed by a combination of pain and swelling. Age, gender, and location were related to the etiopathologic characteristics of the cyst type. A definitive diagnosis can be made on the basis of clinical, radiological, and histological findings, which makes a good interdepartmental relationship between the clinicians and pathologists essential. Knowledge of the biological and histological behavior of the odontogenic cysts is required for their early detection and treatment.
本研究旨在通过研究印度卡纳塔克邦达文盖雷牙科学院口腔颌面病理学系档案中的活检标本,确定牙源性囊肿的流行情况,并确定其临床病理特征。研究数据取自符合世界卫生组织(1992 年)组织学分类的患者病例记录。分析的临床变量包括年龄、性别、解剖位置和组织学诊断。在分析的 2275 份活检报告中,194 例(8.5%)为颌骨囊肿,包括牙源性(6.7%)和非牙源性囊肿(0.25%)。牙源性囊肿包括 69.3%的根囊肿、20.3%的含牙囊肿、5.2%的角化性牙源性囊肿、3.3%的残余囊肿和 1.9%的其他囊肿,如牙周侧囊肿、牙瘤样牙源性囊肿和牙龈囊肿。最常见的临床表现为肿胀,其次是疼痛和肿胀的组合。年龄、性别和位置与囊肿类型的病因病理特征有关。基于临床、放射学和组织学发现可以做出明确诊断,这使得临床医生和病理学家之间建立良好的跨部门关系至关重要。了解牙源性囊肿的生物学和组织学行为对于早期发现和治疗非常重要。